Results 121 to 130 of about 58,665 (304)
Allergy, EarlyView.This study aimed to evaluate the feasibility of extending dupilumab dosing intervals in T2‐CRSwNP by assessing how many patients maintain disease control with once‐every‐12‐weeks (Q12W) dosing and comparing clinical characteristics of super‐responders and excellent responders. Tapering of dupilumab to Q12W appears feasible in super‐responding patients.
P. E. Vonk +13 more
wiley +1 more source
Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders
Andrology, EarlyView.Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret +5 more
wiley +1 more source
Clinical Otolaryngology, EarlyView.ABSTRACT Objectives Smell and taste disorders (SATDs) are frequently overlooked despite growing prevalence. They profoundly impact quality of life. Effective therapies for SATDs remain scarce. This survey aimed to assess patient views surrounding the support available at the time of onset of SATDs, and what further support is needed.
William Ansley +13 more
wiley +1 more source
Immunology, EarlyView.Fully quantitative, mass‐standardised, antibody responses to ten SARS‐CoV‐2 variants show significant variation in immunity profiles or endotypes. The incidence of the complete response to all variants is significantly improved after three vaccinations.
Philip H. James‐Pemberton +6 more
wiley +1 more source
Psychological and Clinical Factors Mediate Post‐COVID‐19 Irritable Bowel Syndrome
Neurogastroenterology &Motility, EarlyView.ABSTRACT Background Exposure to COVID‐19 has been shown previously to be associated with a higher risk for irritable bowel syndrome (IBS). This study aimed to better explain this relationship using mediation analysis. Methods This post hoc analysis of a multicenter cohort study includes 623 patients with and without COVID‐19 infection. All participants
Keren Hod +68 more
wiley +1 more source
Clinical features for diagnosis and management of patients with PRDM12 congenital insensitivity to pain. [PDF]
, 2016 BACKGROUND: Congenital insensitivity to pain (CIP) is a rare extreme phenotype characterised by an inability to perceive pain present from birth due to lack of, or malfunction of, nociceptors.
Ahmed, Mushtaq +7 more
core +3 more sources
Head and Neck Manifestations of Eosinophilic Granulomatosis with Polyangiitis: A Systematic Review. [PDF]
, 2016 OBJECTIVE: To conduct the first and only systematic review of the existing literature on head and neck manifestations of eosinophilic granulomatosis with polyangiitis to guide clinical decision making for the otolaryngologist.
Basnyat, Shristi +4 more
core +1 more source
The UGT2A1/UGT2A2 locus is associated with COVID-19-related anosmia [PDF]
, 2021 Janie F. Shelton +4 more
openalex +1 more source
Journal of Medical Virology, Volume 98, Issue 2, February 2026.ABSTRACT The C19‐YRS was the first condition‐specific for long COVID/post‐COVID syndrome. Although the original C19‐YRS evolved to the modified version (C19‐YRSm) based on psychometric evidence, clinical content relevance, as well as feedback from patients and healthcare professionals, it has not been validated through Rasch analysis. The study aim was
Mike Horton +24 more
wiley +1 more source