Results 71 to 80 of about 49,737 (233)

Six questions on the construction of ontologies in biomedicine [PDF]

, 2005
(Report assembled for the Workshop of the AMIA Working Group on Formal Biomedical Knowledge Representation in connection with AMIA Symposium, Washington DC, 2005.) Best practices in ontology building for biomedicine have been frequently ...
Burgun, A., Ceusters, W., Cimino, J., Davis, J., Elkin, P., Kalet, I., Kumar, Anand, Others, Rector, A., Rice, J., Rogers, J., Smith, Barry   +11 more
core  

“Super‐Responders” to Dupilumab Treatment in Patients With Primary Diffuse Chronic Rhinosinusitis With Nasal Polyps

Allergy, EarlyView.
This study aimed to evaluate the feasibility of extending dupilumab dosing intervals in T2‐CRSwNP by assessing how many patients maintain disease control with once‐every‐12‐weeks (Q12W) dosing and comparing clinical characteristics of super‐responders and excellent responders. Tapering of dupilumab to Q12W appears feasible in super‐responding patients.
P. E. Vonk, J. J. Otten, H. B. E. Elzinga, R. J. L. van der Lans, G. F. J. P. Adriaensen, L. B. L. Benoist, D. R. Hoven, W. J. Fokkens, S. Reitsma, PolyREG Consortium, A.B. Rinia, I. Krebbers, I.J. Kleiss, M. E. Cornet   +13 more
wiley   +1 more source

The Impact of Olfactory Disorders in the United Kingdom [PDF]

, 2014
Olfactory disorders are believed to affect 5% of the general population and have been shown to bear significant psychosocial consequences to sufferers. Although more common than blindness and profound deafness in the United Kingdom, the impact of these ...
Aschenbrenner, Blomqvist, Bramerson, Br  merson, C. M. Philpott, Chalke, Croy, D. Boak, Damm, Deems, Ferris, Frasnelli, Hastan, Haxel, Hummel, Landis, Landis, McNeill, Miwa, Murphy, Nordin, Santos, Shu, Singleton, Temmel, Toller, Vennemann, Wysocki   +27 more
core   +1 more source

The relationship between anosmia and ageusia with biochemical markers, severity, and duration of the disease in patients with COVID-19

Journal of Craniomaxillofacial Research, 2023
Introduction: Due to the increasing prevalence of COVID-19 and its effects on the sense of taste and smell, we analyzed Blood electrolyte levels and biomarkers in COVID-19 patients who have a sign of anosmia and ageusia in Zanjan, Iran, and its ...
Ahmadreza Rasouli, Mashhoud Taghiloo, Hamid Khederlou, Fatemeh Moradi, Zahra Rostami, Mohammad Jafarzadeh, Houshang Bavandpour Karvane, Karim Parastouei   +7 more
doaj  

Diagnosis of Anosmia in Middle Age, But Not in Older Adulthood, Increases Alzheimer Dementia Risk [PDF]

Clinical and Experimental Otorhinolaryngology
Objectives. Many studies have reported that patients with anosmia exhibit an increased incidence of dementia later in life. However, most of these studies have focused exclusively on individuals aged 65 or older, leaving a gap in research on middle-aged ...
Jin Kook Kim, Jae Hoon Cho
doaj   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, EarlyView.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Kallmann syndrome: a hystorical, clinical and molecular review [PDF]

, 2008
Kallmann syndrome (KS), the association of hypogonadotropic hypogonadism and anosmia, was described by Maestre de San Juan in 1856 and characterized as a hereditary condition by Franz Josef Kallmann in 1944.
Albuisson J, Bagatell CJ, Bardin CW, Bauman A, Bulow HE, Chryssikopoulos A, Davidson TM, De Morsier G, Dode C, Dode C, Dode C, Doty RL, Filippi G, Franco B, Fromantin M, Gonzalez-Martinez D, Gonzalez-Martinez D, Groth C, Hardelin JP, Hebert JM, Hipkin LJ, Julio Abucham, Kadva A, Kallmann FJ, Kramer PR, Legouis R, Li M, Lin DC, Maestre de San Juan A, Matsuo T, Mayston MJ, Meitinger T, Miura K, Muenke M, Muller-Hill B, Naftolin F, Okubo K, Oliveira LM, Parenti G, Pawlowitzki IH, Pitteloud N, Pitteloud N, Pitteloud N, Quinton R, Quinton R, Quinton R, Rezvani I, Ribeiro RS, Rogol AD, Rogério Silicani Ribeiro, Rowe RC, Rugarli EI, Sato N, Schwanzel-Fukuda M, Schwanzel-Fukuda M, Seminara SB, Simon MA, Soussi-Yanicostas N, Soussi-Yanicostas N, Trarbach EB, Trarbach EB, Vermeulen A, Waldstreicher J, Wray S   +63 more
core   +3 more sources

Investigating the Effect of Tumour Necrosis Factor Antagonist on Olfaction

Clinical Otolaryngology, EarlyView.
ABSTRACT Objectives Tumour Necrosis factor antagonists is a potent anti‐inflammatory medication and has shown to improve olfactory function in murine models. The primary aim was to determine the effect of TNF antagonists on olfactory performance in humans.
Andreas Espehana, George Macfarlane, Elizabeth Mairenn Garden, Liam Lee, Gabija Klyvyte, Lavandan Jegatheeswaran, Rebecca Davies, Carl Philpott   +7 more
wiley   +1 more source

Schwannoma of the nasal septum-a case report [PDF]

, 2012
Schwannomas of the nasal cavity and paranasal sinuses are very rare. We report the case of a50-year-old woman with a schwannoma arising from the nasal septum.
Felix, Vinod, Janardhanan, Sunil, Kulothungan, Kulothungan   +2 more
core   +1 more source

The Role of ACE2 Receptors of the Olfactory System in Anosmia in COVID-19: An Overview

Neurology Research International, 2021
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019 (COVID-19). The latest data show that more than 211.7 million people were infected and more than 4.4 million deaths have been reported.
Mohammad Javad Nasr, Ali Alizadeh Khatir, Arefeh Babazadeh, Soheil Ebrahimpour   +3 more
doaj   +1 more source