Results 41 to 50 of about 455,213 (268)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Living Spatial Movement of Relation. Reconceptualising Ricœur’s Oneself as Another and Heidegger’s Being and Time

open access: yesÉtudes Ricoeuriennes / Ricoeur Studies, 2021
Beyond the disparate and mainly fleeting references to life in Ricoeur’s Oneself as Another, whether as life as power, living well and with others, or as Ricoeur’s attempt to develop a concept of embodied subjectivity as flesh, which is presumably living
Paul Downes
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Gray Codes Generation Algorithm and Theoretical Evaluation of Random Walks in N-Cubes

open access: yesMathematics, 2018
In previous works, some of the authors have proposed a canonical form of Gray Codes (GCs) in N-cubes (hypercubes of dimension N). This form allowed them to draw an algorithm that theoretically provides exactly all the GCs for a given dimension N.
Sylvain Contassot-Vivier   +2 more
doaj   +1 more source

Imagining ecology: species/energy/dimension in nineteenth-century speculative fiction

open access: yes, 2023
Carroll, SiobhanThis dissertation dwells in the fictional ecologies imagined by Romantic and Victorian authors. It revisits the relationship between nineteenth-century literature and science through speculative fiction (an expansive category of non ...
O'Donnell, Megan E.
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Another essential dimension of priorities: Spatial heterogeneity and temporal stability of climate refugia

open access: yesGlobal Ecology and Conservation
Prioritization analysis with climate dynamics has become a critical, complex, and popular topic for conservation planning, providing opportunities for achieving co-benefits of climate stabilization, biodiversity conservation, and other goals.
Zhibo Du   +7 more
doaj   +1 more source

A Global Poincaré inequality on Graphs via a Conical Curvature-Dimension Condition

open access: yesAnalysis and Geometry in Metric Spaces, 2018
We introduce and study the conical curvature-dimension condition, CCD(K, N), for finite graphs.We show that CCD(K, N) provides necessary and sufficient conditions for the underlying graph to satisfy a sharp global Poincaré inequality which in turn ...
Lakzian Sajjad, Mcguirk Zachary
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

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