Results 251 to 260 of about 1,981,243 (338)

GSDMD deficiency attenuates BPD by suppressing macrophage pyroptosis and promoting M2 polarization. [PDF]

Cell Death Discov
Yang X, Wang X, Yang Y, Ma Y, Liu X, Mo D, Guo C, Han W.   +7 more
europepmc   +1 more source

A Bayesian explanation of machine learning models based on modes and functional ANOVA [PDF]

Quan Long
openalex   +1 more source

Substrate Stress Relaxation Regulates Cell‐Mediated Assembly of Extracellular Matrix

Advanced Functional Materials, EarlyView.
Silicone‐based viscoelastic substrates with tunable stress relaxation reveal how matrix mechanics regulates cellular mechanosensing and cell‐mediated matrix remodelling in the stiff regime. High stress relaxation promotes assembly of fibronectin fibril‐like structures, increased nuclear localization of YAP and formation of β1 integrin‐enriched ...
Jonah L. Voigt, Jens Timmer, Elisabetta Ada Cavalcanti‐Adam   +2 more
wiley   +1 more source

The lncRNA PARylator promotes PARP1 activation and resistance to DNA‑damaging therapy in esophageal squamous cell carcinoma. [PDF]

Exp Hematol Oncol
Qi TF, Liu Y, Yang J, Yue YM, Han MM, Liu H, Li J, Liu M, Zhang Y, Kou JH, Li WJ, Liu X, La T, Liu T, Chen S, Zhang XD, Cang S, Teng L, Fan T.   +18 more
europepmc   +1 more source

Mechanically Tunable Bone Scaffolds: In Vivo Hardening of 3D‐Printed Calcium Phosphate/Polycaprolactone Inks

Advanced Functional Materials, EarlyView.
A 3D bone scaffold with osteogenic properties and capable of hardening in vivo is developed. The scaffold is implanted in a ductile state, and a phase transformation of the ceramic induces the stiffening and strengthening of the scaffold in vivo. Abstract Calcium phosphate 3D printing has revolutionized customized bone grafting.
Miguel Mateu‐Sanz, Pablo Varela, Laura del‐Mazo‐Barbara, Irene Lodoso‐Torrecilla, Emilio Jiménez‐Piqué, Jordi Franch, Miguel Alaminos, Maria‐Pau Ginebra   +7 more
wiley   +1 more source

Appraisal of Readability in Patient-Facing Resources for the Inspire Hypoglossal Nerve Implant. [PDF]

Laryngoscope Investig Otolaryngol
Abell BD, Smith CF, Richards PQ, Boyd JT, Johnson AP.   +4 more
europepmc   +1 more source

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Agonist signaling drives neutrophil subpopulations to promote/inhibit colorectal cancer liver metastasis. [PDF]

Nat Commun
Xu Z, Feng H, Feng W, Zhang Y, Huo J, Xu Z, Chen F, Gao H, Lv Z, Liu W, Tuersun A, Yu S, Li W, Zong Y, Shen X, Cheng X, Zhao J, Lu A.   +17 more
europepmc   +1 more source

DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption

Advanced Functional Materials, EarlyView.
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim, Dai‐Hwan Kim, Priyannth R. Sundharbaabu, Chae Yeon Lee, Jina Bae, Jiyu Hyun, Young‐Ju Jang, Haeni Kim, Min‐Ho Hong, Juewen Liu, Tobias Fey, Suk Ho Bhang, Jun Hyuk Heo, Jung Heon Lee   +13 more
wiley   +1 more source

Physiological oxygen levels reset K⁺ channel activity in human vascular endothelial cells. [PDF]

Redox Biol
Yang F, Wheeler-Crawford A, McIntyre A, Mann GE, Steinert JR.   +4 more
europepmc   +1 more source