Results 261 to 270 of about 1,981,243 (338)
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato +9 more
wiley +1 more source
Targeting PTPN13 with 11-amino-acid peptides of C-terminal APC prevents immune evasion of colorectal cancer. [PDF]
Ma WH +21 more
europepmc +1 more source
Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li +10 more
wiley +1 more source
LncRNA DANCR Activates p38/mTOR-Mediated Autophagy via ANXA2 to Exacerbate Oxygen-Induced Retinal Neovascularization in Mice. [PDF]
Wang Y, Bai J, Zhao S.
europepmc +1 more source
Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim +4 more
wiley +1 more source
The gut vagal sensory pathway drives postprandial sleep via activation of PVH-projecting GABAergic neurons in the NTS. [PDF]
Chen K +8 more
europepmc +1 more source
A programmable interpenetrating double‐network architecture, created via 3D‐TIPS printing and resin infusion, synergistically combines thermoplastic and thermosetting elastomers to balance structural rigidity and surface softness—crucial for paediatric laryngeal stents.
Elizabeth F. Maughan +14 more
wiley +1 more source
LEAFY demonstrates functions in reproductive development of the gametophyte but not the sporophyte of the fern Ceratopteris richardii. [PDF]
McConnell H +8 more
europepmc +1 more source
This work presents the first example of multifunctional protein eutectogels based on a tannic acid: betaine low‐transition‐temperature mixture, exhibiting elastomeric behavior, strong adhesion to various substrates, including biological tissues, and notable anti‐inflammatory properties derived from the natural polyphenol and zwitterion.
Sergio Martin‐Saldaña +8 more
wiley +1 more source

