Results 101 to 110 of about 277,878 (301)
CHD8‐Dependent Chromatin Licensing Sustains Trophoblast Stem Cell Transcriptional Programs
Advanced Science, EarlyView.In this study, Huang et al., identify chromatin remodeler CHD8 as an essential factor in TSC maintenance and placental development. CHD8‐dependent chromatin accessibility supports the occupancy of key trophoblast TFs and is coupled to KMT2A‐associated H3K4me3 deposition at TSC stem and cell cycle genes, providing a permissive chromatin environment for ...
Yuanyuan Huang +16 more
wiley +1 more source
Flexible protein folding by ant colony optimization [PDF]
, 2008 Protein structure prediction is one of the most challenging topics in bioinformatics. As the protein structure is found to be closely related to its functions, predicting the folding structure of a protein to judge its functions is meaningful to the ...
Hu, X. +5 more
core +1 more source
Shear‐Mode Direct Piezoelectric Response of Ferroelectric Nematic Liquid Crystals
Advanced Science, EarlyView.Periodic shear‐induced electric current measurements are reported on two archetypic ferroelectric nematic liquid crystal compounds. From the temperature, frequency and shear angle dependent results of the first and second harmonic current signals together with temperature and oscillatory rheology measurements, the effective piezoelectric coupling ...
Péter Salamon +4 more
wiley +1 more source
Recent advances of privacy-preserving machine learning based on (Fully) Homomorphic Encryption
Security and SafetyFully Homomorphic Encryption (FHE), known for its ability to process encrypted data without decryption, is a promising technique for solving privacy concerns in the machine learning era. However, there are many kinds of available FHE schemes and way more
Hong Cheng
doaj +1 more source
Wearable E‐Textiles for Cardiovascular Monitoring: Materials, Devices, and Integrated Systems
Advanced Science, EarlyView.The graphical abstract highlights the role of conductive materials and textile fabrication techniques in enabling smart textiles for cardiovascular applications. It showcases textile‐based ECG monitoring, pulse sensing, hemodynamic monitoring, and cardiovascular tissue engineering, while emphasizing the challenges and design considerations that govern ...
Bangul Khan +3 more
wiley +1 more source
Advanced Science, EarlyView.A developmentally guided protocol reproducibly specifies EN1‐positive ventral midbrain dopaminergic (vmDA) progenitors from human pluripotent stem cells and yields functional vmDA neurons. Optogenetic induction of α‐synuclein aggregation elicits selective degeneration of TH‐positive neurons in 2D cultures and 3D neurospheroids, while transplanted ...
Heechang Moon +12 more
wiley +1 more source
Acta Haematologica Oncologica TurcicaAim: This study aimed to assess the real-world performance of elranatamab in terms of its effectiveness, safety, and tolerability among patients diagnosed with triple-class refractory-multiple myeloma (TCR-MM) who have undergone extensive prior treatment.
Ant Uzay
doaj +1 more source
Advanced Science, EarlyView.DAIMS is a multimodal model for treatment stratified risk and survival assessment in colorectal cancer. Training draws on pathology, genomics, and clinical reports, yet inference requires only whole slide images, and adaptation to new cohorts proceeds without target survival outcomes.
Chuangjie Cao +15 more
wiley +1 more source
Adoption of emerging ICTs: The role of actors in a social network
Cogent Business & Management, 2016 This paper uses actor network theory (ANT) to provide further insight into ICT adoption framework by showing how the diverse actors in small service(s) businesses guarantee continuous adoption of emerging ICT amidst many influences.
Hart O. Awa, Ojiabo Ukoha, Best C. Eke
doaj +1 more source