Results 141 to 150 of about 1,330,035 (332)

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou   +30 more
wiley   +1 more source

Investigation of suture surgery with ant by Hakim Mohammad the Iranian surgeon of Safavid Era (1501 to 1736)

open access: yesJournal of Current Oncology and Medical Sciences, 2023
Hakim Mohammad, a military physician, and surgeon of the Safavid Era (1501 to 1736) and the author of Dhakhira-Yi-Kamilah book, served as a young man in the Ottoman Empire Officer as a surgeon physician.
Saeed Sepehrikia   +2 more
doaj  

Programmable and Reversible 3D‐to‐3D Shape Transformation: Hierarchical Multimodal Morphing Based on Liquid Crystal Elastomers

open access: yesAdvanced Science, EarlyView.
Hierarchical multimodal 3D‐to‐3D shape morphing is achieved in liquid crystal elastomer‐elastomer bilayers via programmable mismatch strains. Combining pre‐stretch and thermal actuation enables reversible transformations with non‐zero Gaussian curvature, empowering over 30 complex configurations for biomimetic camouflage, adaptive robotics, and dynamic
Jiayu Tian   +4 more
wiley   +1 more source

The role of dopamine in foraging decisions in social insects

open access: yesFrontiers in Insect Science
Animals often need to make decisions about whether to confront risks, and climate change is making these decisions even more critical by increasing environmental stress.
Dajia Ye   +2 more
doaj   +1 more source

Multiscale Cell–Cell Interactive Spatial Transcriptomics Analysis

open access: yesAdvanced Science, EarlyView.
In this study, we present the MultiScale Cell‐Cell Interactive Spatial Transcriptomics Analysis method, which unites the strengths of spatially resolved deep learning techniques with a topological representation of multi‐scale cell‐cell similarity relations.
Sean Cottrell, Guo‐Wei Wei
wiley   +1 more source

Long‐term prognosis is associated with residual disease after neoadjuvant systemic therapy but not with initial nodal status

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
This long‐term follow‐up study determined survival rates in a Swedish national cohort of 417 patients with breast cancer who all had neoadjuvant systemic therapy (NAST). Sentinel lymph node biopsy (SLNB) was performed before NAST in clinically node‐negative and after NAST in clinically node‐positive patients.
L. Zetterlund   +4 more
wiley   +1 more source

Utilizing Proteolytic‐Resistant Nano‐Short Peptide Based on Naphthyl Tail‐Anchored to Combat Bacterial Infections

open access: yesAdvanced Science, EarlyView.
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy