Results 121 to 130 of about 21,256 (264)

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

open access: yesiMetaOmics, EarlyView.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang   +16 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

open access: yesInterdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li   +7 more
wiley   +1 more source

A new approach to assessment for young children referred by education professionals for socio‐emotional, behavioural, and cognitive difficulties

open access: yesJCPP Advances, EarlyView.
Abstract Background Young children with emerging mental health problems and neurodevelopmental differences often do not receive the support they need early in life, and if they do receive support, it may not be appropriately targeted towards their individual needs.
Amy L. Paine   +13 more
wiley   +1 more source

Body weight in autism spectrum disorder: A systematic review and meta‐analysis

open access: yesJCPP Advances, EarlyView.
Abstract Background Evidence on the relationship of autism spectrum disorder (ASD) to overweight/obesity and underweight is mixed. Moreover, it is unclear how this relationship changes with age. Methods We carried out a systematic review (SR) with meta‐analysis on the association between ASD and obesity, overweight and underweight across the life span.
Victoria Nieuwenhuys‐Ruiz   +8 more
wiley   +1 more source

An efficient deep learning model for brain tumour detection with privacy preservation

open access: yesCAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Internet of medical things (IoMT) is becoming more prevalent in healthcare applications as a result of current AI advancements, helping to improve our quality of life and ensure a sustainable health system. IoMT systems with cutting‐edge scientific capabilities are capable of detecting, transmitting, learning and reasoning.
Mujeeb Ur Rehman   +8 more
wiley   +1 more source

Mind the gap! Integrating taxonomic approaches to assess ant diversity at the southern extreme of the Atlantic Forest. [PDF]

open access: yesEcol Evol, 2017
Hanisch PE   +6 more
europepmc   +1 more source

Identifiable regional and neural network abnormalities in early childhood anxiety

open access: yesJCPP Advances, EarlyView.
Abstract Background Although the neural underpinnings of anxiety have been investigated, most research has been confined to adolescence and adulthood, with less of a focus on the early childhood period. Little is known about the role of anticipatory fear processing early childhood, which is a sensitive period for anxiety development.
Khalil I. Thompson   +7 more
wiley   +1 more source

Improved Post‐Processing Framework for Whole Slide Imaging and 3D Reconstruction

open access: yesMicroscopy Research and Technique, EarlyView.
Workflow for 3D reconstruction of marmoset whole‐slide histology. Individual tiles undergo vignette correction to address illumination artifacts before stitching into full‐section images. Sections are then reconstructed using the Possum framework, with a level‐set method incorporated at the nonlinear deformable stage to stabilize alignment and reduce ...
Emily L. De Leon Alvarado   +8 more
wiley   +1 more source

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