Results 91 to 100 of about 26,342 (343)

A portable explosive detector based on fluorescence quenching of pyrene deposited on coloured wax-printed μpADs [PDF]

open access: yes, 2013
A new technique for the detection of explosives has been developed based on fluorescence quenching of pyrene on paper-based analytical devices (μPADs). Wax barriers were generated (150 °C, 5 min) using ten different colours. Magenta was found as the most
Beavis, A   +5 more
core   +1 more source

Physiologically Based Pharmacokinetic (PBPK) Model to Predict the Magnitude of Drug–Drug Interaction Between Fezolinetant and CYP1A2 Inhibitors

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Fezolinetant is a non‐hormonal, selective neurokinin 3 receptor antagonist approved in multiple countries including the United States, in Europe, and in Asia for the treatment of moderate to severe vasomotor symptoms in menopausal women. Fezolinetant is primarily metabolized by CYP1A2 and was found to be a sensitive substrate for CYP1A2 ...
Mary P. Choules   +4 more
wiley   +1 more source

Regulating Food and Drug Companies Privately: A View of Lanham Act Cases Brought Against FDA-Regulated Products [PDF]

open access: yes, 2012
The Lanham Act provides a flexible self-help remedy to food and drug companies that are harmed by unfair competition in the marketplace. But is it desirable for private litigation to become the de facto regulation of the industry?
Lantieri, Paul
core  

Re‐evaluation of calcium silicate (E 552), magnesium silicate (E 553a(i)), magnesium trisilicate (E 553a(ii)) and talc (E 553b) as food additives [PDF]

open access: yes, 2018
The EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re‐evaluating the safety of calcium silicate (E 552), magnesium silicate (E 553a) and talc (E 553b) when used as food additives.
Afzal   +44 more
core   +2 more sources

An infant with Kawasaki disease having gastrointestinal bleeding due to multiple gastric ulcers

open access: yesJournal of General and Family Medicine, EarlyView.
Abstract Kawasaki disease (KD) is an acute systemic vasculitis managed mainly through intravenous immunoglobulin (IVIG), aspirin, and steroids. Although gastrointestinal symptoms are common, gastrointestinal bleeding is rare. We present the case of an 11‐month‐old girl with incomplete KD who developed severe gastrointestinal bleeding due to multiple ...
Takeru Kanazawa   +3 more
wiley   +1 more source

Liver abscess following ingestion of a foreign object [PDF]

open access: yes, 2013
A 31 year old, previously healthy female presented to A&E on 24/07/2012 with a 2 day history of colicky epigastric pain and spiking fever; however on investigation no pathology was found except for an ovarian cyst of 4cm.
Abela, Lauren, Borg Xuereb, Keith
core  

Marburg hemorrhagic fever in Durba and Watsa, Democratic Republic of the Congo: clinical documentation, features of illness, and treatment [PDF]

open access: yes, 2007
The objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77
Antoine Tshomba   +20 more
core   +2 more sources

Effect of food or antacid on pharmacokinetics and pharmacodynamics of febuxostat in healthy subjects.

open access: yesBritish Journal of Clinical Pharmacology, 2008
UNLABELLED What is already known about this subject. Febuxostat is a novel nonpurine selective inhibitor of xanthine oxidase. What this study adds. This is the first manuscript to address the effect of food and antacid on the pharmacokinetics and/or ...
R. Khosravan   +4 more
semanticscholar   +1 more source

Blended diets and effects on gastrointestinal symptoms in children with gastrostomy tubes: A survey study

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Interest is growing in the use of blended diets (BD) in children with gastrostomy. Evidence supporting the benefits of BD is conflicting, with limited data to assist physicians in clinical practice. The present survey aims to evaluate current use of BD in children and adolescents with gastrostomy. Methods An online survey evaluating
Elena Scarpato   +8 more
wiley   +1 more source

Antacid preparations in the modern treatment of acid-base disorders

open access: yesМедицинский совет, 2014
Until the middle of the XX century, a large group of drugs called antacids played the key role in the treatment of acid-related diseases. Antacids have long been used to relieve heartburn and pain in the upper gastrointestinal tract.
S. A. Babanov, E. B. Grischenko
doaj   +1 more source

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