Results 181 to 190 of about 559,284 (318)

Fibroblast Activation Protein Promotes Thoracic Aortic Dissection via PLAUR/ITGB1‐Mediated Pro‐inflammatory Macrophage Polarization

Advanced Science, EarlyView.
This study reveals that FAP promotes thoracic aortic dissection (TAD) through a nonenzymatic mechanism involving fibroblast‐macrophage crosstalk via the FAP/PLAUR/ITGB1/FAK axis. Targeting this pathway might offer a promising therapeutic strategy for TAD.
Hongqiao Zhu, Jianlie Wu, Ziyi Xu, Yifei Pei, Zaiping Jing, Jian Zhou, Rui Feng, Junjun Liu   +7 more
wiley   +1 more source

Case Report: Behavioral analysis guided intervention targeting triggers and urges in skin-picking disorder with comorbid onychophagia. [PDF]

Front Psychiatry
Kawahito M, Murayama K, Tomiyama H, Kato K, Nakao T.   +4 more
europepmc   +1 more source

Leadership and Environmental Sustainability: An Integrative Conceptual Model of Multilevel Antecedents and Consequences of Leader Green Behavior [PDF]

Hannes Zacher, Clara Kühner, Ian M. Katz, Cort W. Rudolph   +3 more
openalex   +1 more source

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

The antecedents and outcomes of teachers' autonomy satisfaction: A meta-analytic investigation. [PDF]

Appl Psychol Health Well Being
Chen Y, Li JB, Yin H, Wang H.
europepmc   +1 more source

An Exploration of the Antecedents to Effective Recommender System Message Design

, 2020
Constantinos K. Coursaris, Antoine Falconnet, Caroline Berger, Wietske Van Osch, Joerg Beringer, Sylvain Sénécal, Pierre‐Majorique Léger   +6 more
openalex   +1 more source

Supply-side Antecedents of dropout rates in MBA programs

, 2020
Víctor Iglesias Argüelles, Montserrat Entrialgo, Frank Müller   +2 more
openalex   +2 more sources

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

Advanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño, Víctor M. de la Oliva Roque, Javier‐Ignacio Ramirez‐Lopez, David P. Kreil, Joaquín Dopazo, Carlos Loucera   +5 more
wiley   +1 more source

Trauma Prevention Care in Natural Disaster-prone Areas: Concept Analysis. [PDF]

Acta Med Philipp
Wijoyo EB, Mustikasari.
europepmc   +1 more source