Results 41 to 50 of about 53,270 (253)

A Visualization Template for the Graphical Representation of Sport Injury Antecedents and Consequences Models and Data

open access: yesJournal of Functional Morphology and Kinesiology, 2020
A template for visually representing factors affecting and affected by the occurrence of sport injury is presented. The visualization template is designed to facilitate comparison among graphic depictions of models and data pertaining to the antecedents ...
Britton W. Brewer, Travis P. Van Brewer
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Employee Engagement and its Dynamics: An Empirical Study of an Information Technology Company Sri Lanka

open access: yesInternational Journal of Academe and Industry Research, 2021
An engaged employee is the most valuable asset of any organisation for they are the key drivers of business activities. This empirical study aims to analyse the relationship between the variable of employee engagement and its antecedents.
Sanduni Tharika   +2 more
doaj   +1 more source

Antecedents of Bon

open access: yesRevue d'Études Tibétaines, 2022
There is no or desperately little reliable early evidence to support the historicity of the grand pre-Buddhist Bon Zhang zhung Empire of later Bon po sources and their western aficionados. Imagination is nonetheless plentiful. In the PIATS 2016, I discuss the oldest historical textual sources relevant to a heartland of Bon, which is variously ...
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Presenting the model of antecedents affecting moral-emotional acting in education [PDF]

open access: yesمدیریت و چشم انداز آموزش
The aim of the current research is to identify and rank the antecedents affecting moral-emotional acting in education. This research was applicable in terms of its purpose, and was carried out with a quantitative approach with an exploratory design.
arefeh kazemi malekmahmoudi   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Antecedents of purpose in life: Evidence from a lagged exposure-wide analysis

open access: yesCogent Psychology, 2020
Potential antecedents to having a sense of purpose in life remain understudied. As researchers begin contemplating purpose as a promising target of public health intervention, it is critical to identify its antecedents.
Ying Chen   +3 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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