Results 131 to 140 of about 1,180,061 (268)

Differences in characteristic morphological variability among distal femurs based on sex and ethnicity. [PDF]

Bone Jt Open
Ammoury N, Dunbar MJ, D'Alessio J, Astephen Wilson J.   +3 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Effect of Tear Film Stability on Variability of Posterior Corneal Curvature Readings with a Swept-Source Optical Biometer in Cataract Patients. [PDF]

Clin Ophthalmol
Muzyka-Wozniak M, Kaminska I, Piwowarczyk PK, Szczesna-Iskander DH.   +3 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

How I do it: exoscopic minimally invasive pericranial flap harvest for endoscopic anterior skull base reconstruction. [PDF]

Acta Neurochir (Wien)
Wiedmann MKH, Steineger JE, Dahlberg D, Dheyauldeen S.   +3 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Trans-symphyseal fixation for complex anterior pelvic fractures: a novel technique guide and case series. [PDF]

OTA Int
Quercetti NF, DiStefano S, Yayac M, Getchell J, Ng MK.   +4 more
europepmc   +1 more source

Anterior

, 2011
[ES] Definición del término Anterior en el diccionario Dicter. [EN] Definition of the word Anterior in the dictionary Dicter.
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A Novel Protocol to Accelerate Functional Orthopedic Treatment Using Low-Intensity Pulsed Ultrasound in Patients With Skeletal Class II Malocclusion: A Preliminary Clinical Report. [PDF]

Cureus
Almrayati DM, Hajeer MY, Burhan AS, Almahdi WH, Jaber ST.   +4 more
europepmc   +1 more source