Results 71 to 80 of about 1,418,276 (316)

Anterior Chamber of the Eye [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Changing Strategies in Keratoplasty After Corneal Hydrops: From Penetrating to Lamellar Approaches – A Narrative Review

Clinical Ophthalmology
Rafah Fairaq,1 Omar Kirat,1 Mohammed AlMutlak,1 Muhammad A Ahad,1 Omar Khan,1,2 Ahmed AlDayel,1 Saud Abdulbadie Khan,2 Mozon Alshareef,3 Wejdan Saeed Alghamdi,1 Halah Bin Helayel1 1Anterior Segment Division, King Khalid Eye Specialist Hospital, Riyadh ...
Fairaq R, Kirat O, AlMutlak M, Ahad MA, Khan O, AlDayel A, Khan SA, Alshareef M, Alghamdi WS, Bin Helayel H   +9 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Comparison of Surgical Outcomes of Graft Survival Rate Using Surgeon Cut versus Precut DSAEK Tissue

Clinical Ophthalmology
Rawan Hawsawi,1 Rafah Fairaq,1 AbdulAziz Mohammed Alrabah,2 Mohammed Al Mutlak1 1Anterior Segment Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; 2Eye Bank Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi ...
Hawsawi R, Fairaq R, Alrabah AM, Al Mutlak M   +3 more
doaj  

Performance and Safety of a Sodium Hyaluronate, Xanthan Gum, and Osmoprotectants Ophthalmic Solution in the Treatment of Dry Eye Disease: An Observational Clinical Investigation

Ophthalmology and Therapy
Introduction Dry eye disease (DED) is characterized by an imbalance in the tear film, resulting in symptoms such as dryness, redness, and discomfort. The management of DED involves tear supplements, medications, or surgery in severe cases.
Mercedes Molero Senosiaín, Barbara Burgos-Blasco, Pilar Perez-García, Álvaro Sánchez-Ventosa, Marta Villalba-González, María Dolores López Pérez, José Carlos Díaz, Vanesa Díaz-Mesa, Alberto Villarrubia Cuadrado, Enrique Artiaga Elordi, Jose Manuel Larrosa Poves, Alejandro Blasco, Antonio Mateo, Claudine Civiale, Laura Bonino, Antonio Cano-Ortiz   +15 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Outcomes of Repeat Deep Anterior Lamellar Keratoplasty in Keratoconus: Case Series

Clinical Ophthalmology
Omar Kirat,1 Rafah Fairaq,1 Mohammed AlMutlak,1 Raneem S AlQahtani,2 Ghadah A AlHussein,2 Sara AlHilali1 1Anterior Segment Division, King Khaled Eye Specialist Hospital and Research Center, Riyadh, Saudi Arabia; 2Surgery Department, Aldiriyah Hospital ...
Kirat O, Fairaq R, AlMutlak M, AlQahtani RS, AlHussein GA, AlHilali S   +5 more
doaj  

Early Real-World Outcomes with a Novel Hybrid Full Range of Vision Intraocular Lens

Medicina
Background and Objectives: We aimed to describe early real-world visual, refractive, and safety outcomes following implantation of a novel hybrid full range of vision intraocular lens (IOL) in patients undergoing cataract surgery.
Gerardo Valvecchia, Tomás M. Castro, Diana E. Calero-Vera, Manuela Masseroni, Nazarena Nasif, Eddie Icaza, Lucas Aguirre, Nicolás Vargas, Gastón Gómez-Caride, Luciano Perrone   +9 more
doaj   +1 more source