Results 221 to 230 of about 12,916,357 (311)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Low Rate of Periprosthetic Femoral Fracture in Dorr Type B and C Femurs With the Anterior Approach Using Stems Cemented According to the "French Paradox". [PDF]

Arthroplast Today
Laboudie P, Sadoun M, Falkenrodt C, Hallé A, Anract P, Hamadouche M.   +5 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Nerve injuries in cervical spine surgery via anterior approach: a comprehensive review. [PDF]

J Spine Surg
Hasan S, Farmer N, Arefi I, Hagood M, Gadangi P, Alqasmi H, Waheed M, Shafau AL, Abusabha Y, Saleh E, Khalil J, Elgafy H.   +11 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Anterior approach and robotic assistance associated with shorter operative times and lower transfusion requirements in conversion total hip arthroplasty. [PDF]

Eur J Orthop Surg Traumatol
Riley R, Lutnick E, Frappa N, Geiger J, Simpson A, Leininger A, Dyskin E.   +6 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Pseudoaneurysm of the profunda femoris artery following direct anterior approach total hip arthroplasty: a report of two cases. [PDF]

J Surg Case Rep
Huang Q, Li X, Wang Y, Zhu W.
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Clinical outcomes of internal iliosciatic fixation using a conventional reconstruction plate via an anterior approach for acetabular fractures involving the posterior column. [PDF]

Arch Orthop Trauma Surg
Xiong H, Chen H, Cao S, Chen X, Wang F.
europepmc   +1 more source