Results 281 to 290 of about 85,673 (335)

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

open access: yesAdvanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon   +10 more
wiley   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

open access: yesAdvanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao   +6 more
wiley   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Platelet Rubicon Bidirectional Regulation of GPVI and Integrin αIIbβ3 Signaling Mitigates Stroke Infarction Without Compromising Hemostasis

open access: yesAdvanced Science, EarlyView.
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen   +11 more
wiley   +1 more source
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Anterior chamber depth studies

Journal of Cataract and Refractive Surgery, 2015
To compare the anterior chamber depth (ACD; corneal epithelium to lens) using 3 modalities and compare the change 1 day and 3 months postoperatively.Private practice, Santa Monica, California, USA.Nonrandomized prospective series.The mean optical pachymetry and immersion ultrasound (US) of the ACD and partial coherence interferometry (PCI) were ...
Kenneth J, Hoffer, Giacomo, Savini
openaire   +2 more sources

Management of Anterior Chamber Depth After Trabeculectomy

American Journal of Ophthalmology, 1988
We followed up 36 eyes of 34 patients for the first three months after trabeculectomy, paying special attention to the depth of the anterior chamber. A significant difference in postoperative course was noted between those eyes with central cornea-lens touch and those with cornea-iris touch but not contact between cornea and lens.
W C, Stewart, M B, Shields
  +7 more sources

Determining postoperative anterior chamber depth

Journal of Cataract and Refractive Surgery, 2003
To compare measured and calculated postoperative anterior chamber depths (ACDs).Department of Ophthalmology and Institute of Medical Physics, University of Vienna, Vienna, Austria, and Department of Ophthalmology, University of Mainz, Mainz, Germany.The postoperative ACD was measured in 189 pseudophakic eyes using a laboratory prototype of partial ...
Katharina, Kriechbaum   +5 more
openaire   +2 more sources

Axial Anterior Chamber Depth after Trabeculectomy

Ophthalmologica, 1990
Trabeculectomy was performed on 14 consecutive phakic eyes, and measurements of axial anterior chamber depth were taken preoperatively and on postoperative days 1, 2, 3, 6 and 14. The mean maximal change in anterior chamber depth occurred on the 1st postoperative day, while the anterior chamber reached its shallowest state on the 2nd postoperative day.
K, Goins, T, Smith, R, Kinker, J, Lewis
openaire   +2 more sources

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