Results 31 to 40 of about 39,504 (293)

Axial Length, Anterior Chamber Depth-A Study in Different Age Groups and Refractive Errors [PDF]

Journal of Clinical and Diagnostic Research, 2013
Introduction: Axial length and anterior chamber depth play an important role in refractive status of the eye in different age groups. Material and Methods: The present study has been done on 240 patients (480 eyes) who attended eye OPD of Department
Veena Bhardwaj, Gandhi Parth Rajeshbhai
doaj   +1 more source

Change in anterior chamber depth before and after phacoemulsification in eyes with a short axial length-a quasi-experimental trial

Journal of the Pakistan Medical Association
Objective: To determine changes in anterior chamber depth following phacoemulsification in eyes with a short axial length. Method: The quasi-experimental study was conducted at the Department of Ophthalmology and Visual Sciences, Aga Khan University ...
Dania Memon, Khadijah Abid, Hina Israr Qazi, Shaukat Ali Chhipa   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Comparative study of surgical outcomes of twin-site phacotrabeculectomy with mitomycin C in primary open-angle glaucoma versus primary angle-closure glaucoma

Indian Journal of Ophthalmology, 2023
Purpose: To compare the surgical outcomes of twin-site phacotrabeculectomy with Mitomycin C (MMC) in primary open-angle glaucoma (POAG) versus primary angle-closure glaucoma (PACG). Methods: Prospective, comparative, observational study.
Devendra Maheshwari, Madhavi Ramanatha Pillai, Swathi Kanduri, Indu J Nair, Mohideen Abdul Kader, Rengappa Ramakrishnan   +5 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Agreement between ANTERION and IOLMaster700 in ocular biometric measurements in a Brazilian population [PDF]

Revista Brasileira de Oftalmologia
Objective: To evaluate the agreement of biometric parameters measured by the ANTERION and IOLMaster700 devices in a Brazilian population, considering statistical differences and their clinical relevance.
Luís Armando Vitorino Alves de Souza Gondim, Roberta Kern Menna Barreto, José Maurilio Tavares de Lucena, Bernardo Kaplan Moscovici, Ivan Corso Teixeira   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Phenotypic distribution of anterior chamber depth for (BXD24b X CAST) N2 mice.

, 2023
Phenotypic distribution of anterior chamber depth for (BXD24b X CAST) N2 mice.
Michael G. Anderson (11031443), Demelza R. Larson (16884007), Allysa J. Kimber (16884010), Kacie J. Meyer (11031431)   +3 more
core   +1 more source