Results 161 to 170 of about 172,666 (300)

Disrupted Brain Structure and Function in Alzheimer's Disease Patients With Behavioral and Psychological Symptoms

open access: yesiNew Medicine, EarlyView.
ABSTRACT Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in Alzheimer's disease (AD), but the underlying mechanisms are unclear. This study aims to elucidate the neuropathological mechanisms underlying BPSD by investigating gray matter volume (GMV) and brain connectivity in AD patients with and without BPSD.
Xuerui Pang   +8 more
wiley   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

open access: yesInterdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li   +24 more
wiley   +1 more source

Neural correlates of resilience to trauma during adolescence: A multi‐modal study

open access: yesJCPP Advances, EarlyView.
Abstract Background Understanding resilience mechanisms is important for advancing early intervention strategies, yet research on the neurobiology of resilience in adolescents is limited. The present study examined the brain structural and resting‐state functional connectivity (rsFC) correlates of resilience to internalizing and externalizing symptoms ...
Lu Zhang   +3 more
wiley   +1 more source

Reward processing in children with affective dysregulation

open access: yesJCPP Advances, EarlyView.
Abstract Background Affective dysregulation (AD) in children is characterized by irritability, anger, and frequent intense temper outbursts. Considerable evidence implies altered processing of frustration about missed rewards, but few studies investigated the preceding and thus potentially predictive reward anticipation and initial delivery processing ...
Pascal‐M. Aggensteiner   +11 more
wiley   +1 more source

Enhancing spatial cognition through origami training: Insights from brain connectomes

open access: yesJournal of Intelligent Medicine, EarlyView.
Origami training enhances spatial cognition via measurable brain network changes (EEG/eye‐tracking). The mental rotation and folding tasks validate these gains. This low‐cost method offers a scalable intervention for cognitive decline. Abstract Spatial cognition is a key ability of human cognition and intelligence.
Xiuyun Liu   +13 more
wiley   +1 more source

Anterior cingulate cortex

open access: yes, 2018
Rishabh Verma   +2 more
openaire   +1 more source

The Role of Magnetic Resonance Spectroscopy (MRS), Diffusion‐Tensor‐Imaging (DTI) and Structural MRI in the Alzheimer's Disease and Mild Cognitive Impairment Diagnosis: A Review

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca   +3 more
wiley   +1 more source

Spatiotemporal dynamics of brain function network during proprioception rehabilitation after anterior cruciate ligament reconstruction: A randomized trial

open access: yesKnee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
The improvement of proprioceptive function after ACLR is related to the optimization of spatiotemporal dynamics of SM, CC, DM, CB and VI functional networks. Rehabilitation optimization can incorporate visual–cognitive dual‐task exercises. Abstract Purpose In this study, we aimed to examine the dynamic functional network connectivity (dFNC) patterns ...
Xiaoyun Zhuang   +7 more
wiley   +1 more source

Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes   +6 more
wiley   +1 more source

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