Results 211 to 220 of about 1,380,198 (292)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

An angiographic study on the morphometry of the anterior communicating artery complex- a South African sample. [PDF]

Surg Radiol Anat
Madolo M, Gunston G, More S, Mpolokeng K.   +3 more
europepmc   +1 more source

ATP Citrate Lyase in Metabolic Disease: Mechanistic Insights and Clinical Potential

iNew Medicine, EarlyView.
ATP citrate lyase (ACLY) is a central metabolic hub that diverts mitochondrial citrate to fuel de novo lipogenesis, cholesterol biosynthesis, and protein acetylation. Given its robust correlation with pathological changes in multiple human diseases, ACLY inhibitors featuring distinct pharmacological strengths have been developed for therapeutic ...
Wenbiao Wang, Xinyan Li, Honglu Shi, Gaolei Song, Zhifu Xie, Jingya Li   +5 more
wiley   +1 more source

A Case of Coil Embolization for an Angiographically Occult Ruptured Anterior Communicating Artery Aneurysm. [PDF]

J Neuroendovasc Ther
Iwabuchi N, Tashiro R, Shoji K, Ezura M, Sato K, Endo H.   +5 more
europepmc   +1 more source

S100A9 promotes pulmonary arterial hypertension by regulating mitochondria–endoplasmic reticulum interaction‐mediated inflammatory injury of endothelial cells

Interdisciplinary Medicine, EarlyView.
Macrophage‐derived S100 calcium‐binding protein A9 (S100A9) promotes the pathological progression of pulmonary arterial hypertension (PAH). S100A9 upregulates the interaction between signal‐transducing adaptor protein 2 and leucine‐rich repeat kinase 2, thereby regulating mitochondria–endoplasmic reticulum (ER) contact.
Chen Gong, Long Chen, Yiting Zhao, Xiaohe Wang, Qiang Yuan, Xiaofeng Fang, Liuyi Li, Yinbo Xu, Shumei Jiang, Guangwen Xu, Ke Meng, Delong Wang, Kangli Cao, Jianlong Sheng, Liling Guo, Shichun Shen   +15 more
wiley   +1 more source

X-configuration Pipeline Flex embolization device for complex anterior communicating artery aneurysm: illustrative case. [PDF]

J Neurosurg Case Lessons
Zhu H, Wang Y, Liu Y, Wu Y, Gao G.
europepmc   +1 more source

Lateral supraorbital approach for large olfactory groove meningioma and unruptured large anterior communicating artery aneurysm: operative video and technical considerations. [PDF]

Neurosurg Focus Video
Watanabe N, de Los Santos V, Jiang T, Fava A, El Mostarchid M, Froelich S.   +5 more
europepmc   +1 more source

Autonomous Velocity Encoding (VENC) Selection Improves Precision of Quantitative Flow Measurement

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The optimal velocity encoding limit (VENC) in phase contrast MRI is subject‐specific because it depends on peak flow rate and the presence of flow jets. Currently, VENC is set manually with limited prior knowledge of the peak velocity. Setting the correct VENC might improve measurement precision or shorten scan times.
Pierre Daudé, Rajiv Ramasawmy, Christine Mancini, Dominique Franson, Sunggun Lee, Anastasia Tsakirellis, W. Patricia Bandettini, Ahsan Javed, Kelvin Chow, Adrienne E. Campbell‐Washburn   +9 more
wiley   +1 more source

Preliminary Experience with Extradural Clinoidectomy and Lamina Terminalis Fenestration in Anterior Communicating Artery Aneurysm Surgery: A Matched Case-Control Study. [PDF]

J Clin Med
Sadigh Y, Schouten JW, van Putten EHP, Dammers R, Volovici V.   +4 more
europepmc   +1 more source

Clinical Value and Research Prospects of 1024 Matrix Optimization in 64‐Slice Cerebral CTA for Perforating Artery Visualisation

Journal of Medical Radiation Sciences, EarlyView.
This letter comments on Nagumo et al.'s study evaluating 1024‐matrix reconstruction for intracranial perforating artery visualisation in 64‐slice cerebral CTA, affirming its cost‐effective value for standard CT scanners (https://doi.org/10.1002/jmrs.70055).
Yang Liu, Wei Wu
wiley   +1 more source