Tissue engineering for tendon and ligament repair: Insights and advances
Tendon and ligament injuries are widespread diseases, leading to severe pain and a consequent reduced mobility. This phenomenon is mainly due to the limited ability to self‐healing of these tissues. Unfortunately, the currently available surgical and rehabilitative treatments suffer frequent complications and incomplete success.
Francesca Romano +3 more
wiley +1 more source
Simultaneous anterior cruciate ligament reconstruction with valgus high tibial osteotomy improves mid- to long-term clinical outcomes without increasing the complication rates in young anterior cruciate ligament deficient patients with varus malalignment: a systematic review and meta-analysis. [PDF]
Han G, Li F, Xu Q, Qi P.
europepmc +1 more source
Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang +16 more
wiley +1 more source
Inverted Cyclops Lesion Following Anterior Cruciate Ligament Repair: A Case Report. [PDF]
Litten R +5 more
europepmc +1 more source
Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy
Cerebral palsy, caused by non‐progressive brain injury, is frequently accompanied by skeletal muscle alterations. This review synthesizes current evidence from muscle biopsy studies, revealing cellular and molecular adaptations in muscle tissue. Abstract Cerebral palsy (CP), the most prevalent childhood‐onset motor disability, frequently entails ...
Sebastian Edman +4 more
wiley +1 more source
Are decorin gene variants associated with anterior cruciate ligament rupture susceptibility? [PDF]
Łosińska K +3 more
europepmc +1 more source
Anatomical morphometrics have been used to design and manufacture models of the flexor digitorum profundus tendon to bone insertion in vitro. This innovative approach can be used to design models of other enthesis regions with anatomical and clinical applicability.
Jeremy W. Mortimer +2 more
wiley +1 more source
Influence of the Medial and Lateral Posterior Tibial Slope on Anterior Tibial Translation During Gait in Anterior Cruciate Ligament-Deficient Knees. [PDF]
El Kayali MKD +8 more
europepmc +1 more source
Effect of human myoblasts on tenogenic progression in 2D and 3D culture models
We investigated whether factors released from muscle derived myogenic cells enhance tenogenic progressions of human tendon derived cells using two‐dimensional (2D) culture model and a three‐dimensional (3D)‐engineered tendon construct culture model.
Yoshifumi Tsuchiya +3 more
wiley +1 more source

