Results 41 to 50 of about 852,040 (284)

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira   +8 more
wiley   +1 more source

Single and Double Bundle Arthroscopic Reconstruction of Anterior Cruciate Ligament (Review of Literature)

open access: yesActa Biomedica Scientifica, 2019
Researches performed in the past 20 years show the necessity of the restoration of anatomic position of anterior cruciate ligament as the main stabilizing structure of the joint in combination with the restoration of other injured elements and correction
D. B. Balzhinimaev   +2 more
doaj   +1 more source

Anterior Cruciate Ligament Injury [PDF]

open access: yesSports Health: A Multidisciplinary Approach, 2015
Despite more than 40 years of clinical focus on the anterior cruciate ligament (ACL)–injured knee, a complete understanding of the injury mechanism, the optimal treatment plan (including reconstruction), and the best protocol for rehabilitation continue to stimulate much debate.
openaire   +2 more sources

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

open access: yesAdvanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang   +6 more
wiley   +1 more source

Osseous femoral avulsion of the anterior cruciate ligament origin in an adult

open access: yesRadiology Case Reports, 2015
Injuries of the anterior cruciate ligament are commonly encountered in clinical practice, and occur in a wide variety of settings, from sports-related injuries to polytrauma. Tears of the anterior cruciate ligament supersede osseous avulsion in the adult
Samir H. Shah, MD   +3 more
doaj   +1 more source

Ligament Reconstruction in Patients Operated Arthroscopically with Bone-Patellar Bone Graft Using Lysholm Score

open access: yesPakistan Armed Forces Medical Journal, 2023
Objective: To assess the mean Lysholm score after arthroscopic anterior cruciate ligament Anterior Cruciate Ligament (ACL) reconstruction with a bone-patellar tendon-bone graft. Study Design: Prospective longitudinal study.
Khalil Ur Rehman   +5 more
doaj   +1 more source

In Situ Profiling of Nanoscale Strains Uncovers Mechano‐Architectural Predictors of Aging and Osteoarthritis Emergence

open access: yesAdvanced Science, EarlyView.
In situ mechanical loading of osteoarthritis‐prone murine knee joints reveals that spatial alterations in subchondral plate microarchitecture precede cartilage loss and promote a shift from coordinated epiphyseal strain dissipation in healthy joints to focal subchondral strain concentration in osteoarthritis‐prone joints.
Aikta Sharma   +10 more
wiley   +1 more source

Spontaneous healing of a ruptured anterior cruciate ligament: a case series and literature review

open access: yesJournal of Experimental Orthopaedics, 2023
Purpose The anterior cruciate ligament is probably one of the ligaments with the lowest healing potential. Many authors have reported cases of spontaneous healing but nowadays it is difficult to predict successful healing of an anterior cruciate ligament
Leonardo Previ   +7 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

A Review on Biomechanics of Anterior Cruciate Ligament and Materials for Reconstruction

open access: yesApplied Bionics and Biomechanics, 2018
The anterior cruciate ligament is one of the six ligaments in the human knee joint that provides stability during articulations. It is relatively prone to acute and chronic injuries as compared to other ligaments.
M. Marieswaran   +4 more
doaj   +1 more source

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