Results 111 to 120 of about 49,722 (359)

Post-traumatic osteoarthritis in mice following mechanical injury to the synovial joint [PDF]

open access: yes, 2017
We investigated the spectrum of lesions characteristic of post-traumatic osteoarthritis (PTOA) across the knee joint in response to mechanical injury.
Chinzei, Nobuaki   +7 more
core   +3 more sources

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor   +7 more
wiley   +1 more source

Revision Anterior Cruciate Ligament, Posterior Cruciate Ligament, and Medial Collateral Ligament Reconstructions With Primary Fibular Collateral Ligament Reconstruction After First-Stage Bone Grafting Procedure

open access: yesArthroscopy Techniques
Revision multiligament knee injuries are rare but can occur due to unaddressed injuries in the primary reconstruction, poor tunnel placement, or a new injury.
Luke V. Tollefson, B.S.   +4 more
doaj   +1 more source

Relationship between Tibial conformation, cage size and advancement achieved in TTA procedure [PDF]

open access: yes, 2018
Previous studies have suggested that there is a theoretical discrepancy between the cage size and the resultant tibial tuberosity advancement, with the cage size consistently providing less tibial tuberosity advancement than predicted.
AA Fettig   +27 more
core   +2 more sources

Clinical Feasibility of Deep Learning Contrast Synthesis From MR Fingerprinting in Knee Osteoarthritis

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Magnetic Resonance Fingerprinting (MRF) enables rapid quantitative parameter mapping from which synthetic clinical contrast images can be derived using deep learning (DL). Purpose This study evaluates the reliability and interchangeability of MRF‐derived synthetic knee MRI relative to conventional MRI in patients with osteoarthritis.
Mika T. Nevalainen   +9 more
wiley   +1 more source

Melatonin Exerts Chondroprotective Effects Against Osteoarthritis by Promoting PI3K/AKT/FoxO3‐Mediated Mitophagy

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a prevalent degenerative joint disease. This study combines bioinformatics analysis with in vivo and in vitro experiments to elucidate the molecular mechanisms through which melatonin (MT) regulates mitophagy to alleviate OA.
Chao Huang   +4 more
wiley   +1 more source

Accuracy of Magnetic Resonance Imaging in Diagnosis of Anterior Cruciate Ligament and Meniscus Tear: An Observational Study

open access: yesJournal of Nepal Medical Association
Introduction: Magnetic resonance imaging is used for the diagnosis of anterior cruciate ligament and meniscus tears but its value in the diagnosis of these pathologies is limited.
Sushil Thapa   +4 more
doaj   +1 more source

Extracellular Vesicle‐Mediated Communication Between Anterior Cruciate Ligament and Bone Marrow Cells Modulates Hamstring Tenocyte Behavior and Apoptosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Following anterior cruciate ligament (ACL) reconstruction, enhancing hamstring tenocyte activity and minimizing apoptosis are critical for preventing graft failure and promoting ligamentization. This study investigated the therapeutic potential of extracellular vesicles (EVs) derived from a coculture of ACL remnant cells and bone marrow ...
Hon‐Lok Lo   +5 more
wiley   +1 more source

A Review on Biomechanics of Anterior Cruciate Ligament and Materials for Reconstruction

open access: yesApplied Bionics and Biomechanics, 2018
The anterior cruciate ligament is one of the six ligaments in the human knee joint that provides stability during articulations. It is relatively prone to acute and chronic injuries as compared to other ligaments.
M. Marieswaran   +4 more
doaj   +1 more source

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