Results 221 to 230 of about 67,974 (348)

Tissue engineering for tendon and ligament repair: Insights and advances

open access: yesVIEW, EarlyView.
Tendon and ligament injuries are widespread diseases, leading to severe pain and a consequent reduced mobility. This phenomenon is mainly due to the limited ability to self‐healing of these tissues. Unfortunately, the currently available surgical and rehabilitative treatments suffer frequent complications and incomplete success.
Francesca Romano   +3 more
wiley   +1 more source

Cognitive-Motor Function During Jump Landings After Anterior Cruciate Ligament Reconstruction. [PDF]

open access: yesOrthop J Sports Med
Aflatounian F   +5 more
europepmc   +1 more source

Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis

open access: yesCell Proliferation, EarlyView.
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang   +16 more
wiley   +1 more source

Ultrasound Evaluation of the Regenerating Tendon of the Semitendinosus After Harvest for Anterior Cruciate Ligament Reconstruction. [PDF]

open access: yesJ Clin Med
Becciolini M   +8 more
europepmc   +1 more source

Microscopic and molecular aspects of skeletal muscle alterations in cerebral palsy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Cerebral palsy, caused by non‐progressive brain injury, is frequently accompanied by skeletal muscle alterations. This review synthesizes current evidence from muscle biopsy studies, revealing cellular and molecular adaptations in muscle tissue. Abstract Cerebral palsy (CP), the most prevalent childhood‐onset motor disability, frequently entails ...
Sebastian Edman   +4 more
wiley   +1 more source

Anatomical design and production of a novel three‐dimensional co‐culture system replicating the human flexor digitorum profundus enthesis

open access: yesJournal of Anatomy, EarlyView.
Anatomical morphometrics have been used to design and manufacture models of the flexor digitorum profundus tendon to bone insertion in vitro. This innovative approach can be used to design models of other enthesis regions with anatomical and clinical applicability.
Jeremy W. Mortimer   +2 more
wiley   +1 more source

Effect of human myoblasts on tenogenic progression in 2D and 3D culture models

open access: yesJournal of Anatomy, EarlyView.
We investigated whether factors released from muscle derived myogenic cells enhance tenogenic progressions of human tendon derived cells using two‐dimensional (2D) culture model and a three‐dimensional (3D)‐engineered tendon construct culture model.
Yoshifumi Tsuchiya   +3 more
wiley   +1 more source

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