Results 181 to 190 of about 40,688 (307)

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Long-Term Stability and Safety of Orthognathic-Orthodontic Correction for Skeletal Anterior Open Bite: A Systematic Review and Evidence Appraisal. [PDF]

Cureus
Obeisi AH, Alanazi MM, Natto SB, Alsalmi HA, Alzahrani AA, Alotaibi RA, Aljari AA, Alzahrani SB, Alamri FB, Mohammed Alghamdi AF, Katib HS.   +10 more
europepmc   +1 more source

Tooth size discrepancy in orthodontic patients with skeletal anterior open bite. [PDF]

Clin Exp Dent Res, 2022
Al Maaitah EF, Al-Madani N, Abu Alhaija ES.   +2 more
europepmc   +1 more source

Temporal and Cell‐Specific Regulation of Synaptic Homeostasis by the Chromatin Remodeler Chd1

Advanced Science, EarlyView.
Chd1, the Drosophila homologue of mammalian CHD2 ‐ a gene linked to autism, epilepsy, and intellectual disability, is required for synaptic homeostatic plasticity. Chd1 in glia is necessary for the rapid induction of synaptic homeostasis, whereas Chd1 in motoneurons, muscle, and glia is critical for long‐term maintenance.
Danielle T. Morency, Tao Cui, Yimei Cai, Chloe Lok, Rachel E. Nokku, Ruoxian Huang, Grace L. Chu, Yumeng Xie, Saleem W. Abu‐Tayeh, Kaikai He, Chengjie Qiu, Junyi Wang, Paxton M. Paganelli, Ting Wang, Gabrielle Williams, Sreejith Nair, Huadong Pei, Dion K. Dickman, Stefano Vicini, Tingting Wang   +19 more
wiley   +1 more source

Correction of Anterior Open Bite Using Temporary Anchorage Devices: A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Burgos-Lancero P, Ibor-Miguel M, Marqués-Martínez L, Boo-Gordillo P, García-Miralles E, Guinot-Barona C.   +5 more
europepmc   +1 more source

Orthodontic treatment of children with anterior open bite and posterior crossbite: An analysis of the stomatognathic system. [PDF]

J Oral Biol Craniofac Res, 2023
Gonçalves LMN, Palinkas M, Regalo IH, Gonçalves PN, de Vasconcelos PB, Matsumoto MAN, Siéssere S, Regalo SCH.   +7 more
europepmc   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

A Novel Treatment Modality Using Miniplates for Skeletal Class II Malocclusion with Anterior Open Bite: A Case Report. [PDF]

Int J Clin Pediatr Dent
Shreya S, Shetty R, Shetty V, Gore I, Bhosale TB.   +4 more
europepmc   +1 more source

Correction of anterior open bite of varying severity using clear aligner therapy-A case series. [PDF]

Clin Case Rep, 2022
Sabouni W, Venugopal A, Adel SM, Vaid N.
europepmc   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source