Results 231 to 240 of about 16,967 (296)

Femtosecond‐Laser‐Induced Physical Unclonable Random Maze Structure for Storage‐Free Encryption

Advanced Science, EarlyView.
Femtosecond‐laser‐induced gold random maze structures serve as multimodal physical unclonable functions for storage‐free encryption. Their stochastic optical, electrical, and Raman responses are generated by plasmon‐assisted Marangoni formation and converted into AES‐compatible keys without permanent secret‐key storage, offering a portable route toward
Shiru Jiang, Hongliang Li, Shengjie Ma, Sang‐Shin Lee, Lei Wang, Mengyun Hu, Heping Zeng   +6 more
wiley   +1 more source

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

Evaluation of Dimensional Changes in Maxillary and Frontal Sinus in Adult Patients With Anterior Open Bite and Normal Overbite: A Retrospective Cone Beam Computed Tomography (CBCT) Study. [PDF]

Cureus
R S S S, Khan N, Parameswaran R, Boovaraghavan S, Nagi M.   +4 more
europepmc   +1 more source

Anterior open bite: A scoping review

International Journal of Applied Dental Sciences
Gabriela Garcia Gonzalez, Nelly Alejandra Rodriguez Guajardo, Gloria Martha Alvarez Morales, Fatima Del Muro Casas, Maria Argelia Akemi Nakagoshi Cepeda, Patricia Medina Santos, Jose Aurelio Cortina Aguilar, Nahomi Yamileth Silva Sanmiguel, Juan Manuel Solis Soto   +8 more
openaire   +1 more source

Anterior open bite: aetiology and management

Dental Update, 2011
Anterior open bite has a multi-factorial aetiology comprising: genetically inherited skeletal pattern, soft tissue effect and digit-sucking habits. To formulate an appropriate treatment plan, accurate diagnosis is essential. Simple open bites may sometimes resolve completely during the transition from mixed to permanent dentition, if the digit-sucking
Paul Jonathan, Sandler, Arun K, Madahar, Alison, Murray   +2 more
openaire   +3 more sources

Orthodontic treatment of anterior open bite.

International journal of paediatric dentistry, 2008
To review the currently available treatment options of anterior open bite.Search all major dental journals and literature on treatment and management of anterior open bite. Medline search (1960-2006). Literature and data on treatment and management of anterior open bite with keywords 'open bite', 'anterior open bite', 'orthodontic treatment', 'long ...
Chui Shan Teresa, Ng, Wing Kit Ricky, Wong, Urban, Hagg   +2 more
openaire   +3 more sources

Etiology and pathogenesis of anterior open bite: a review.

East African medical journal, 2012
To review the etiology and pathogenesis of anterior open bite malocclusion.Review of literature was affected through Pubmed, Google scholar and Science direct. References identified from articles found from the primary search were also reviewed.Published data on etiology and pathogenesis of anterior open bite over the last five decades (1960-2009) were
Wanjau, J, Sethusa, MPS
openaire   +5 more sources