Results 41 to 50 of about 16,288,237 (292)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Ocorrência de maloclusões em pré-escolares de 2 a 5 anos de idade, Florianópolis, SC, Brasil [PDF]

open access: yes, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.Objetivo: Este trabalho propõe verificar a ocorrência de mordida aberta anterior, overjet acentuado, mordida cruzada posterior e associar essas maloclusões
Macari, Kerli
core  

Anterior open bite treatment using Balters class II bionator: a case report

open access: yes, 2023
There are several reasons for the onset of malocclusion, which promotes disharmonious development of the craniofacial structure and may involve various factors such as incorrect positioning of teeth, maxilla, mandible, lips, tongue, and/or cheeks ...
Maria Beatriz Tavares da Costa
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Sucking habits and anterior open bite among Venezuelan and Brazilian children

open access: yesBrazilian Journal of Oral Sciences, 2010
Culturally different population groups have distinct infant feeding practices, which presumably may be related to diverse occlusal features in the primary dentition.
Andréia Carvalho Cardoso   +3 more
doaj   +1 more source

Associação da ocorrência de maloclusões com fatores socioeconômicos em pré-escolares do município de Florianópolis/sc [PDF]

open access: yes, 2015
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.O objetivo do presente estudo foi avaliar a associação entre a ocorrência de maloclusão em pré-escolares e a classe econômica de suas famílias.
Laurentino, Marina Petry
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

A review of the management of anterior open bite malocclusion

open access: yesAustralasian Orthodontic Journal, 1990
Abstract Anterior openbite (AOB) malocclusion is considered one of the most demanding challenges for the orthodontist, as occlusal correction is difficult, facial aesthetics may be unsatisfactory and the incidence of relapse is high.
Lawry Denise M.   +3 more
openaire   +3 more sources

Management of anterior open-bite in the deciduous, mixed and permanent dentition stage: a descriptive review

open access: yes, 2021
Anterior open bite is one of the most complex malocclusions to manage. The interaction of skeletal, dental, and soft tissue effects can contribute to develop an anterior open bite.
Marinelli G.   +16 more
core   +1 more source

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