Results 1 to 10 of about 64,507 (169)

EpCAM Is a Surface Marker for Enriching Anterior Pituitary Cells From Human Hypothalamic-Pituitary Organoids [PDF]

open access: yesFrontiers in Endocrinology, 2022
Human stem cell-derived organoid culture enables the in vitro analysis of the cellular function in three-dimensional aggregates mimicking native organs, and also provides a valuable source of specific cell types in the human body.
Yu Kodani   +13 more
doaj   +2 more sources

Dysregulated zinc homeostasis and microadenomas in the anterior pituitary: pathological insights into suicide risk [PDF]

open access: yesFrontiers in Psychiatry
BackgroundSuicide is a significant public health problem influenced by various risk factors, including dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis.
Hiram Tendilla-Beltrán   +8 more
doaj   +2 more sources

An Exploration of Non-Coding RNAs in Extracellular Vesicles Delivered by Swine Anterior Pituitary [PDF]

open access: yesFrontiers in Genetics, 2021
Extracellular vesicles are lipid bilayer-delimited particles carrying proteins, lipids, and small RNAs. Previous studies have demonstrated that they had regulatory functions both physiologically and pathologically. However, information remains inadequate
Jiali Xiong   +8 more
doaj   +2 more sources

Effect of enhanced plane of nutrition in early life on the transcriptome and proteome of the anterior pituitary gland in Angus heifer calves [PDF]

open access: yesBMC Genomics
Background Enhanced nutrition during the early calfhood period has been shown to lead to earlier pubertal development in heifer calves. This is of interest as earlier pubertal onset can subsequently facilitate earlier calving which can economically ...
Kate Keogh   +2 more
doaj   +2 more sources

Ultrastructural characteristics of the anterior pituitary gland of cattle in the definitive period of postnatal ontogenesis [PDF]

open access: yesE3S Web of Conferences, 2021
Today much attention is paid to the study of the pituitary ultrastructure of laboratory animals and humans. But there is not enough available literature to study the most important organ of internal secretion of productive animal.
Khasaev A.N.   +4 more
doaj   +1 more source

Antiapoptotic factor humanin is expressed in normal and tumoral pituitary cells and protects them from TNF-α-induced apoptosis. [PDF]

open access: yesPLoS ONE, 2014
Humanin (HN) is a 24-amino acid peptide with cytoprotective action in several cell types such as neurons and testicular germ cells. Rattin (HNr), a homologous peptide of HN expressed in several adult rat tissues, also has antiapoptotic action.
María Florencia Gottardo   +9 more
doaj   +1 more source

Pituitary-Related Adverse Events and Onset Patterns Caused by Immune Checkpoint Inhibitors: Analysis Using the Japanese Adverse Drug Event Report Database

open access: yesMedicina, 2023
Background and Objectives: One type of immune-related adverse event caused by immune checkpoint inhibitors (ICIs) is pituitary-related adverse events.
Hiroki Asano   +4 more
doaj   +1 more source

Nitric Oxide Plays a Key Role in Ovariectomy-Induced Apoptosis in Anterior Pituitary: Interplay between Nitric Oxide Pathway and Estrogen. [PDF]

open access: yesPLoS ONE, 2016
Changes in the estrogenic status produce deep changes in pituitary physiology, mainly because estrogens (E2) are one of the main regulators of pituitary cell population.
Sonia A Ronchetti   +4 more
doaj   +1 more source

Regulation of Prolactin Release at the End Stage of Chicken Embryogenesis

open access: yesThe Journal of Poultry Science, 2022
Difference of onset of increase of PRL content in the anterior pituitary gland and plasma PRL concentration during the late stage of chicken embryogenesis is well known. To investigate the disagreement, changes in PRL content and PRL mRNA levels, and the
Norio Kansaku   +3 more
doaj   +1 more source

Virus Injection to the Pituitary via Transsphenoidal Approach and the Innervation of Anterior and Posterior Pituitary of Rat

open access: yesFrontiers in Endocrinology, 2020
The theory holds that the anterior pituitary in mammals receives humoral regulation. Previous studies have reported that the pars distalis of the anterior pituitary of several mammalian species contains substance P-, calcitonin gene-related peptide (CGRP)
Xiaohui Li   +9 more
doaj   +1 more source

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