A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance. [PDF]
Fertility depends on the correct maturation and function of approximately 800 gonadotropin-releasing hormone (GnRH) neurons in the brain. GnRH neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates fertility. In adulthood, GnRH
Hoffmann, Hanne M, Mellon, Pamela L
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Developmental and functional effects of steroid hormones on the neuroendocrine axis and spinal cord [PDF]
This review highlights the principal effects of steroid hormones at central and peripheral levels in the neuroendocrine axis. The data discussed highlight the principal role of oestrogens and testosterone in hormonal programming in relation to sexual ...
Gonzalez Deniselle, Maria Claudia+4 more
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Pituitary stalk interruption syndrome (PSIS) is a congenital pituitary anatomical defect. This syndrome is an antenatal developmental defect belonging to the holoprosencephaly phenotype spectrum.
J. Vergier+5 more
semanticscholar +1 more source
The anterior pituitary and reproduction in bats [PDF]
This contribution is a review of investigations on the role(s) of the anterior pituitary in chiropteran reproduction. Information on this subject has come mainly from histological studies of cytological changes during the annual cycle and mostly from hibernating temperate-zone species. Although direct evidence is unavailable, it appears that variations
openaire +3 more sources
ABSTRACT Background Given the association between spontaneous cerebrospinal fluid (sCSF) leak and idiopathic intracranial hypertension (IIH), and the association of IIH and venous sinus stenosis (VSS), we sought to determine the prevalence of VSS in sCSF leak and the role of venous sinus stenting for sCSF leak.
Jenny B. Xiao+6 more
wiley +1 more source
Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue. [PDF]
Two different monoclonal antibodies, characterized initially as binding synaptic terminal regions of rat brain, bind a 65,000-dalton protein, which is exposed on the outer surface of brain synaptic vesicles. Immunocytochemical experiments at the electron
Matthew, WD, Reichardt, LF, Tsavaler, L
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Strategies for optimization of hypoglycemia rat models
This review focuses on rat models for studying the short‐term and long‐term effects of mild and severe hypoglycemia. We explored the physiological mechanisms to understand the consequences of hypoglycemia in rat experimental models. This study sheds light on uncovering the therapeutic potential for hypoglycemic patients and its efficacy in mitigating ...
Lee Yeong Zher+4 more
wiley +1 more source
The Effect of High Dose Total Body Irradiation on ACTH, Corticosterone, and Catecholamines in the Rat [PDF]
Total body irradiation (TBI) or partial body irradiation is a distinct risk of accidental, wartime, or terrorist events. Total body irradiation is also used as conditioning therapy before hematopoietic stem cell transplantation.
Bruder, Eric D.+4 more
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Post‐stroke depression (PSD) animal model of traditional Chinese medicine (TCM) combined with disease and syndrome often uses western medicine surgery (including: middle cerebral artery embolization to construct cerebral ischemia, or brain injection of collagenase to construct cerebral hemorrhage) combined with other methods (including: isolation ...
Jielin Wang+4 more
wiley +1 more source
Onset, timing, and exposure therapy of stress disorders: mechanistic insight from a mathematical model of oscillating neuroendocrine dynamics [PDF]
The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the HPA axis are correlated with many stress-related diseases such as post-traumatic stress disorder (
Chou, Tom+2 more
core +3 more sources