Results 71 to 80 of about 1,079,710 (360)

Pituitary stalk interruption syndrome: A case report

Radiology Case Reports, 2023
Pituitary stalk interruption syndrome (PSIS) is a rare congenital abnormality. It comprises the triad of thin or interrupted pituitary stalk, aplasia or hypoplasia of anterior pituitary gland, and absent or ectopic posterior pituitary gland.
Kapil Dawadi, MD, Prajwal Dahal, MD, Binuda Poudyal, MD   +2 more
doaj  

DNA Origami‐Cyanine Nanocomplex for Precision Imaging of KRAS‐Mutant Pancreatic Cancer Cells

Advanced Science, EarlyView.
DNA origami‐cyanine (Do‐Cy) nanocomplexes are synthesized to selectively image KRAS‐mutant pancreatic cancer cells in the highly desmoplastic tumors. This study shows that the Do‐Cy nanocomplexes are preferentially internalized by cancer cells over other stroma cells via KRAS‐dependent macropinocytosis.
Hye‐ran Moon, Yancheng Du, Sae Rome Choi, Seongmin Seo, Cih Cheng, Bennett D. Elzey, Jong Hyun Choi, Bumsoo Han   +7 more
wiley   +1 more source

A Multiplex Gene Expression Assay for Direct Measurement of RNA Transcripts in Crude Lysates of the Nematode Caenorhabditis elegans Used as a Bioanalytical Tool

Environmental Toxicology and Chemistry, Volume 42, Issue 1, Page 130-142, January 2023., 2023
Abstract Gene expression profiling in Caenorhabditis elegans has been demonstrated to be a potential bioanalytical tool to detect the toxic potency of environmental contaminants. The RNA transcripts of genes responding to toxic exposure can be used as biomarkers for detecting these toxins. For routine application in environmental quality monitoring, an
Antoine Karengera, Cong Bao, Toine F. H. Bovee, Inez J. T. Dinkla, Albertinka J. Murk   +4 more
wiley   +1 more source

Significant Quantitative and Qualitative Transition in Pituitary Stem / Progenitor Cells Occurs during the Postnatal Development of the Rat Anterior Pituitary

Journal of neuroendocrinology, 2011
We reported recently that a pituitary‐specific transcription factor PROP1 is present in SOX2‐positive cells and disappears at the early stage of the transition from progenitor cell to committed cell during the embryonic development of the rat pituitary ...
S. Yoshida, T. Kato, Hideji Yako, Takao Susa, L. Cai, M. Osuna, M. Osuna, Kinji Inoue, Y. Kato   +8 more
semanticscholar   +1 more source

MRI of ectopic posterior pituitary gland with dysgenesis of pituitary stalk in a patient with hypogonadotropic hypogonadism

Radiology Case Reports, 2018
The ectopic posterior pituitary is a rare condition which is characterized by the ectopic location of posterior lobe of pituitary, pituitary stalk abnormalities, and associated clinical manifestations of anterior lobe related growth hormone dysfunction ...
Ashim Kumar Lahiri, Ramanivas Sundareyan, David Jenkins, Anjumara Nilak   +3 more
doaj  

Epileptiform Activity and Seizure Risk Follow Long‐Term Non‐Linear Attractor Dynamics

Advanced Science, EarlyView.
This study leverages the HAVOK framework to model long‐term, nonlinear attractor dynamics underlying epileptiform activity and seizure risk in epilepsy patients. By identifying key forcing mechanisms driving chaotic transitions, the findings improve seizure risk forecasting over multi‐day cycles and provide a pathway for personalized, data‐driven ...
Richard E Rosch, Brittany Scheid, Kathryn A Davis, Brian Litt, Arian Ashourvan   +4 more
wiley   +1 more source

Clinical and Pathological Aspects of Silent Pituitary Adenomas

Journal of Clinical Endocrinology and Metabolism, 2018
Context Silent pituitary adenomas are anterior pituitary tumors with hormone synthesis but without signs or symptoms of hormone hypersecretion. They have been increasingly recognized and represent challenging diagnostic issues.
J. Drummond, F. Roncaroli, A. Grossman, M. Korbonits   +3 more
semanticscholar   +1 more source

Implantable Self‐Powered Systems for Electrical Stimulation Medical Devices

Advanced Science, EarlyView.
In this paper, the design strategy and clinical application of ISS are discussed in depth from four aspects: the design and optimization of the energy collection module, the selection and preparation of adaptive electrode materials, the innovation of system design strategy, and the biological effect of electrical stimulation of ISS.
Xi Cui, Li Wu, Chao Zhang, Zhou Li
wiley   +1 more source

From pituitary adenoma to pituitary neuroendocrine tumor (PitNET): an International Pituitary Pathology Club proposal.

Endocrine-Related Cancer, 2017
The classification of neoplasms of adenohypophysial cells is misleading because of the simplistic distinction between adenoma and carcinoma, based solely on metastatic spread and the poor reproducibility and predictive value of the definition of atypical
Sylvia L. Asa, O. Casar-Borota, Philippe Chanson, Etienne Delgrange, P. Earls, S. Ezzat, Ashley B. Grossman, H. Ikeda, N. Inoshita, N. Karavitaki, M. Korbonits, E. R. Laws, Lopes Mb, N. Maartens, Ian E. McCutcheon, O. Mete, Hiroshi Nishioka, G. Raverot, Federico Roncaroli, W. Saeger, L. Syro, A. Vasiljevic, Chiara Villa, A. Wierinckx, J. Trouillas   +24 more
semanticscholar   +1 more source

Oxytocin‐Mediate Modulation of Splenic Immunosuppression in Chronic Social Stress Through Neuroendocrine Pathways

Advanced Science, EarlyView.
Chronic social stress elevates oxytocin levels, leading to immunosuppression by enhancing regulatory T‐cell activity and promoting anti‐inflammatory macrophage polarization in the spleen. Blocking oxytocin signaling reverses these effects but worsens stress‐induced behavioral disorders and reduces survival rates. This highlights oxytocin's dual role in
Yi‐Shu Zhang, Hai‐Chao Chen, Jia‐Xin Cao, Si‐Wei Zhou, Yue‐Zhang Ma, Yu‐Hong Jing   +5 more
wiley   +1 more source