Results 201 to 210 of about 5,568,025 (289)

Swept Source Optical Coherence Tomography Analysis of the Selected Eye's Anterior Segment Parameters. [PDF]

J Clin Med, 2021
Dembski M, Nowińska A, Ulfik-Dembska K, Wylęgała E.   +3 more
europepmc   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Corneal optical densitometry and anterior segment parameters in healthy upper Egyptian population: a prospective observational cross-sectional study. [PDF]

BMC Ophthalmol
Hamid MA, Esmail MEK, Zein HA.
europepmc   +1 more source

Agreement of axial length and anterior segment parameters measured with the MYAH device compared to Pentacam AXL and IOLMaster 700 in myopic children. [PDF]

Int Ophthalmol, 2023
Sabur H, Takes O.
europepmc   +1 more source

Comparative Analysis of Choroid Plexus Volume Between MOG Antibody Associated Disease and Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Choroid plexus volume (CPV) has been proposed as a neuro‐immunological marker of multiple sclerosis (MS), but its relevance in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) remains uncertain. We analyzed CPV in 43 individuals with MOGAD, 48 with MS, and 44 healthy controls using a Bayesian Gaussian mixture modeling ...
Jae‐Won Hyun, Shaun G. Hong, Na Young Park, Su‐Hyun Kim, Ho Jin Kim   +4 more
wiley   +1 more source

Age- and Sex-Related Normative Anterior Segment Parameters Using Swept-Source OCT: Insights from Pediatric to Elderly Populations. [PDF]

J Clin Med
Sonmez HK, Akkul Z, Sener H, Buyukpatır Deneme E, Er Arslantas E, Evereklioglu C, Horozoglu F, Polat OA, Arda H.   +8 more
europepmc   +1 more source

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Corneal and anterior segment parameters in patients with clinically unilateral pseudoexfoliation syndrome. [PDF]

Med Hypothesis Discov Innov Ophthalmol
Karmiris E, Machairoudia G, Roussou A, Tsiogka A, Chalkiadaki E.   +4 more
europepmc   +1 more source

Response to comments on: Repeatability of Orbscan III for anterior segment parameters in normal eyes. [PDF]

Indian J Ophthalmol, 2021
Sharma M, Jain N, Koshy AS, Arora V, Lalgudi VG.   +4 more
europepmc   +1 more source