Results 121 to 130 of about 809,230 (219)

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Volume 78, Issue 10, Page 1544-1551, October 2026.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello   +5 more
wiley   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

open access: yesArthritis Care &Research, Volume 78, Issue 10, Page 1449-1466, October 2026.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci   +25 more
wiley   +1 more source

The Impact of Caring for a Child With Juvenile Idiopathic Arthritis on Caregiver Quality of Life

open access: yesACR Open Rheumatology, Volume 8, Issue 10, October 2026.
Objective Juvenile idiopathic arthritis (JIA) impacts children and their families, often increasing caregiver burden and diminishing quality of life. This study assessed the care‐related quality of life of parent‐caregivers of children with JIA using the Care‐Related Quality of Life instrument (CarerQol), identified the most affected caregiving ...
Deborah A. Marshall   +105 more
wiley   +1 more source

Monitoring Reactive Oxygen Species‐Induced Cellular Responses in Retinal Pigment Epithelium Cells Using Autofluorescence Multispectral Imaging

open access: yesAdvanced Photonics Research, Volume 7, Issue 10, October 2026.
Autofluorescence multispectral imaging enables label‐free assessment of oxidative stress in retinal pigment epithelial cells by capturing stressor‐specific metabolic signatures. Distinct autofluorescence patterns and redox changes allow classification of cellular stress states across multiple pathways.
Abhilash Goud Marupally   +9 more
wiley   +1 more source

Hyperglycemia‐Induced Microglial CTSS Disrupts Blood‐Retinal Barrier Integrity via PAR2‐Dependent Downregulation of Endothelial MFSD2A

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Hyperglycemia induces retinal microglial activation and CTSS upregulation, disrupting microglia‐endothelial crosstalk via PAR2‐dependent MFSD2A suppression. Abnormal activation of microglia amplifies retinal inflammatory cascade, enhances transcytosis, compromises BRB integrity, and accelerates DR progression.
Chengye Xu   +8 more
wiley   +1 more source

Proteomic Tear Fluid Analysis in Acute Anterior Uveitis Reveals Distinct Characteristics During Active Inflammation

open access: green
Lynn S. zur Bonsen   +16 more
openalex   +2 more sources

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