Results 121 to 130 of about 809,230 (219)
High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis
Arthritis Care &Research, Volume 78, Issue 10, Page 1544-1551, October 2026.Objective
Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods
We identified 10,021 patients with an incident diagnosis Anna Costello, Rui Xiao, Xuemei Zhang, Jahan Jazayeri, Irit R. Rasooly, Pamela F. Weiss +5 morewiley +1 more sourceThe Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases
Arthritis Care &Research, Volume 78, Issue 10, Page 1449-1466, October 2026.Objective
A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce +25 morewiley +1 more sourceThe Impact of Caring for a Child With Juvenile Idiopathic Arthritis on Caregiver Quality of Life
ACR Open Rheumatology, Volume 8, Issue 10, October 2026.Objective
Juvenile idiopathic arthritis (JIA) impacts children and their families, often increasing caregiver burden and diminishing quality of life. This study assessed the care‐related quality of life of parent‐caregivers of children with JIA using the Care‐Related Quality of Life instrument (CarerQol), identified the most affected caregiving ...Deborah A. Marshall, Ana Claudia Fuhrmann, Rodrigo Dal Ben, Gillian R. Currie, Rae S. M. Yeung, Sebastiaan J. Vastert, Nico Wulffraat, Joost F. Swart, Susanne Benseler, on behalf of the UCAN CAN‐DU and UCAN CURE Consortia, Rae Yeung, Shirley Tse, Deborah Levy, Ronald Laxer, Brian Feldman, Jennifer Ji Young Lee, Alisa Rachlis, Susanne Benseler, Nicole Johnson, Muhammed Dhalla, Paivi Miettunen, Heinrike Schmeling, Marinka Twilt, Rebeka Stevenson, Deborah Marshall, Andrea Human, David Cabral, Jaime Guzman, Kim Morishita, Kristin Houghton, Lori Tucker, Tommy Gerschman, Herman Tam, Mercedes Chan, Ross Petty, Roman Jurencak, Nadia Luca, Ciarán Duffy, Tala El Tal, Roberta Berard, Jonathan Park, Erkan Demirkaya, Lily Lim, Adam Huber, Bianca Lang, Elizabeth Stringer, Chelsea DeCoste, Suzanne Ramsey, Dax G. Rumsey, Daniah Basodan, Lillian Lim, Hon Yan Ng, Jeanine McColl, Tara McGrath, Michelle Batthish, Tania Cellucci, Liane Heale, Claire LeBlanc, Gaëlle Chédeville, Rosie Scuccimarri, Sarah Campillo, Piya Lahiry, Paul Dancey, Nickolas Blanchette, Alan Rosenberg, Mehul Jariwala, Tristan Kerr, Kate Neufeld, Clare Hutchinson, Gordon Soon, Dieneke Schonenberg, Mariken Gruppen, Merlijn van den Berg, Giske Biesbroek, Philomine van Pelt, Marleen Verkaaik, Sylvia Kamphuis, Danielle Brinkman, Petra Hissink Muller, Ellen Schatorje, Esther Hoppenreijs, Annet van Royen‐Kerkhof, Sebastiaan Vastert, Berent Prakken, Erika Van Nieuwenhove, Joost Swart, Marc Jansen, Nico Wulffraat, Elizabeth Legger, Wineke Armbrust, Joseph Cafazzo, Maarten IJzerman, Alexander Mosoiu, Amy Xu, Arthur Cheng, Bruno Pereira, Trang Duong, Harper Cheng, Brenleigh Jebb, Gillian R. Currie, Rodrigo Dal Ben, Ravneet Sran, Elodie Boudes, Michelle Kip, Sytze de Rook, Regina de Geus +105 morewiley +1 more sourceMonitoring Reactive Oxygen Species‐Induced Cellular Responses in Retinal Pigment Epithelium Cells Using Autofluorescence Multispectral Imaging
Advanced Photonics Research, Volume 7, Issue 10, October 2026.Autofluorescence multispectral imaging enables label‐free assessment of oxidative stress in retinal pigment epithelial cells by capturing stressor‐specific metabolic signatures. Distinct autofluorescence patterns and redox changes allow classification of cellular stress states across multiple pathways.Abhilash Goud Marupally, Aline Knab, Ayad G. Anwer, Yuan Tian, Shannon Handley, Abbas Habibalahi, Andrew White, Nicole Carnt, Robert Casson, Ewa M. Goldys +9 morewiley +1 more sourceHyperglycemia‐Induced Microglial CTSS Disrupts Blood‐Retinal Barrier Integrity via PAR2‐Dependent Downregulation of Endothelial MFSD2A
CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.Hyperglycemia induces retinal microglial activation and CTSS upregulation, disrupting microglia‐endothelial crosstalk via PAR2‐dependent MFSD2A suppression. Abnormal activation of microglia amplifies retinal inflammatory cascade, enhances transcytosis, compromises BRB integrity, and accelerates DR progression.Chengye Xu, Hongxue Li, Qian Xu, Kangqi Zhao, Yangwen Chen, Yan Wang, Wei Zou, Binglin Kuang, Hongyu Kuang +8 morewiley +1 more sourceProteomic Tear Fluid Analysis in Acute Anterior Uveitis Reveals Distinct Characteristics During Active Inflammation
Lynn S. zur Bonsen, Uwe Pleyer, Dominika Pohlmann, Melis C. Cömert Arisoy, Vadim Farztdinov, Hildrun Haibel, Isabel Kaeferstein, Vitus A. Knecht, Steffen E. Künzel, Michael Mülleder, Fabian Nikolai Proft, Mikhail Protopopov, Valeria Ríos Rodríguez, Anne Rübsam, Murat Torğutalp, Denis Poddubnyy, Judith Rademacher +16 moreopenalex +2 more sources