Results 51 to 60 of about 2,061,103 (249)

Beta adrenergic blokade in myocardial infarction [PDF]

, 1980
This thesis is concerned with the influence of acute and long-term beta-adrenergic blockade on myocardial infarction in man. An original statistical evaluation of all published and some available unpublished clinical trials is presented in Chapter I ...
Yusuf, Salim, Yusuf, S
core   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

Right ventricular involvement in anterior myocardial infarction: a tissue Doppler-derived strain and strain rate study

Clinics, 2013
OBJECTIVE: Strain and strain rate imaging is currently the most popular echocardiographic technique that reveals subclinical myocardial damage. There are currently no available data on this imaging method with regard to assessing right ventricular ...
Osman Sonmez, Mehmet Kayrak, Gokhan Altunbas, Turyan Abdulhalikov, Yusuf Alihanoglu, Ahmet Bacaksiz, Kurtulus Ozdemir, Hasan Gok   +7 more
doaj   +1 more source

Clopidogrel discontinuation after acute coronary syndromes: frequency, predictors and associations with death and myocardial infarction--a hospital registry-primary care linked cohort (MINAP-GPRD). [PDF]

, 2011
AIMS: Adherence to evidence-based treatments and its consequences after acute myocardial infarction (MI) are poorly defined. We examined the extent to which clopidogrel treatment initiated in hospital is continued in primary care; the factors predictive ...
Van Staa, Tjeerd; id_orcid, K. A. A. Fox, Hemingway, Harry, Boggon, Rachael, van Staa, TP, H. Hemingway, Boggon, R, Begg, Alan, Fox, KAA, Ray, KK, Emmas, C, Timmis, A, T. P. van Staa, A. Begg, Begg, A, R. Boggon, C. Emmas, Fox, Keith A A, Fox, Keith AA, Ray, Kausik K, K. K. Ray, Emmas, Cathy, van Staa, Tjeerd P, Timmis, Adam, Hemingway, H, A. Timmis   +25 more
core   +1 more source

Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size [PDF]

, 2021
Aims: Identifying novel mediators of lethal myocardial reperfusion injury that can be targeted during primary percutaneous coronary intervention (PPCI) is key to limiting the progression of patients with ST-elevated myocardial infarction (STEMI) to ...
Mangion, Kenneth, Lee, Mathew MY, Channon, Keith M, Good, Richard, Rocchiccioli, Paul, Nicklin, Stuart A., He, Weihong, Loughrey, Christopher M., Shaukat, Aadil, Petrie, Mark C, Elliott, Elspeth B, Nicklin, Stuart A, Channon, Keith M., Hood, Stuart, Nather, Katrin, Smith, Godfrey L, Elliott, Elspeth B., Carrick, David, Lee, Mathew M.Y., Davie, Andrew, O’Toole, Dylan, Lee, Mathew M Y, McCarroll, Charlotte S., Hawksby, Catherine, Loughrey, Christopher M, Petrie, Mark C., Oldroyd, Keith G., McArthur, Lisa, Martin, Tamara, McEntegart, Margaret, McClure, John, Smith, Godfrey L., Berry, Colin, Zaeri, Ali, Oldroyd, Keith G, Riddell, Alexandra, O'Toole, Dylan, Lindsay, Mitchell M., McCarroll, Charlotte S, Corcoran, David, Watkins, Stuart, Lindsay, Mitchell M, Eteiba, Hany, Ford, Kristopher   +43 more
core   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han, Guolin Miao, Yinqi Zhao, Zhiyong Du, Kaikai Lu, Changqi Xiao, Aiden Xian, Jiaxin Duanmu, Zihao Zhou, Jinxuan Chen, Lianxin Zhang, Chao Zhai, Yitong Xu, Zhaoling Li, Xianqin Shen, Sijing Shi, Jingxuan Chen, Si Mei, Yuan Fang, Liwen Zheng, Ling Zhang, Yuhui Wang, Wei Huang, Erdan Dong, Xunde Xian   +24 more
wiley   +1 more source

Intervention on anomalous left anterior descending artery originating from right coronary sinus

Journal of Indian College of Cardiology, 2020
Coronary arteries anomalies are rare. We report a case of anterior wall myocardial infarction with anomalous left anterior descending artery (LAD) and left circumflex artery (LCX), with LAD originating from right coronary sinus and LCX from right ...
Sandeep Bijapur, B S Arun, C N Manjunath, Prabhavathi Bhat   +3 more
doaj   +1 more source

Effective components screening and anti-myocardial infarction mechanism study of the Chinese medicine NSLF6 based on "system to system" mode [PDF]

, 2012
Background Shuanglong formula (SLF), a Chinese medicine composed of panax ginseng and salvia miltiorrhiza exhibited significant effect in the treatment of myocardial infarction (MI) in clinical. Because of the complex nature and lack of stringent quality
Yuan-Yuan Xie, Chen, Xi, Lv Shu-Feng, Liang, Q-L, Xu, Qing-Bo, Qing-Bo Xu, Liang Qiong-Lin, Cheng, Yi-Jun, Zhang, Q-L, Rong Gao, Xu, Q-B, Yi-Ming Wang, Zhang, Rong-Li, Xue Li, Gao, Rong, Lv, Shu-Feng, Zhang Rong-Li, Shu-Feng Lv, Xu Qing-Bo, Xi Chen, Xue-Mei Fan, Liang, Xiao-Ping, Liang Xiao-Ping, Jun Wu, Wu Jun, Xie Yuan-Yuan, Luo Guo-An, Zhang, Qing-Li, Zhang Hong-Yang, Xiao-Ping Liang, Gao, R, Luo, Guo-An, Xie, Yuan-Yuan, Zhang, Hong-Yang, Cheng, Y-J, Fan Xue-Mei, Zhang Qing-Li, Liang, Qiong-Lin, Xiao, Q-Z, Zhang, H-Y, Xiao, Qing-Zhong, Zhang, R-L, Yi-Jun Cheng, Chen, X, Wu, Jun, Xie, Y-Y, Luo, G-A, Qing-Li Zhang, Qiong-Lin Liang, Wang, Yi-Ming, Qing-Zhong Xiao, Lv, S-F, Gao Rong, Li Xue, Wang, Y-M, Wu, J, Fan, Xue-Mei, Cheng Yi-Jun, Hong-Yang Zhang, Wang Yi-Ming, Fan, X-M, Li, Xue, Liang, X-P, Guo-An Luo, Chen Xi, Xiao Qing-Zhong, Li, X, Rong-Li Zhang   +67 more
core   +1 more source

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

Advanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li, Joanne T. M. Tan, Lei Xiang, Jiandi Liu, Ayla Hoogendoorn, Victoria A. Nankivell, Lauren Sandeman, Richard Le, Rouyan Chen, Robert A. McLaughlin, Peter J. Psaltis, Johan W. Verjans, Christina A. Bursill   +12 more
wiley   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source