Results 1 to 10 of about 6,338 (241)

Preclinical pharmacokinetics and in vitro ADME properties of PAT-1102: a novel HDAC inhibitor for cancer therapy [PDF]

Journal of Cancer Research and Clinical Oncology
Background Histone deacetylases (HDAC) are involved in chromatin remodelling, and histone deacetylases inhibitors have become the interest of research and shown promising antitumor effects against various cancer.
Chandrashekar Mataguru Doreswamy, Srinivas Seekallu, Suresh Babu Venkataramaiah, Mohan Cheluru Umesh, C. Subathra Devi   +4 more
doaj   +2 more sources

Background pharmacological therapy in the ANTHEM‐HF: comparison to contemporary trials of novel heart failure therapies [PDF]

ESC Heart Failure, 2019
Aims Clinical trials of new heart failure (HF) therapies administer guideline‐directed medical therapy (GDMT) as background pharmacologic treatment (BPT).
Rajendra K. Premchand, Kamal Sharma, Sanjay Mittal, Rufino Monteiro, Imad Libbus, Jeffrey L. Ardell, Douglas D. Gregory, Bruce H. KenKnight, Badri Amurthur, Lorenzo A. DiCarlo, Inder S. Anand   +10 more
doaj   +2 more sources

Colombian national anthem as the dialogicity continuum [PDF]

Training, Language and Culture, 2023
National anthems play a crucial role in expressing cultural identity and collective memory. Despite their significance, the study of anthems remains underexplored from cognitive, linguacultural, and discursive perspectives, particularly in the Latin ...
Olga S. Chesnokova
doaj   +1 more source

Doula care across the maternity care continuum and impact on maternal health: Evaluation of doula programs across three states using propensity score matching

EClinicalMedicine, 2022
Summary: Background: This evaluation of doula care emerges at a time when maternal mortality in the U.S. outranks every country in the developed world.
April M. Falconi, Samantha G. Bromfield, Trúc Tang, Demetria Malloy, Denae Blanco, RN Susan Disciglio, RN Winnie Chi   +6 more
doaj   +1 more source

Minimizing bias in massive multi-arm observational studies with BCAUS: balancing covariates automatically using supervision

BMC Medical Research Methodology, 2021
Background Observational studies are increasingly being used to provide supplementary evidence in addition to Randomized Control Trials (RCTs) because they provide a scale and diversity of participants and outcomes that would be infeasible in an RCT ...
Chinmay Belthangady, Will Stedden, Beau Norgeot   +2 more
doaj   +1 more source

Burden of non-alcoholic steatohepatitis among children with type 2 diabetes mellitus

Diabetology & Metabolic Syndrome, 2021
This claims-based retrospective cohort study examined the prevalence and incremental impact of non-alcoholic steatohepatitis among children with type 2 diabetes mellitus in the United States.
Lauren Parlett, Qinli Ma, Qian Shi, Geoffrey Crawford, Laura Herrera Scott, Vincent Willey, Abiy Agiro   +6 more
doaj   +1 more source

PRINSIP NASIONALISME DALAM LIRIK LAGU KEBANGSAAN ARAB SAUDI DAN LAGU KEBANGSAAN INDONESIA (Kajian Sastra Banding)

An-Nahdah Al-'Arabiyah, 2022
This study aims to describe the construction of the principle of nationalism in two different national anthems, namely the national anthem of Saudi Arabia and the national anthem of Indonesia.
Fharis Romanda
doaj   +1 more source

Revisiting the dynamic risk profile of cardiovascular/non‐cardiovascular multimorbidity in incident atrial fibrillation patients and five cardiovascular/non‐cardiovascular outcomes: A machine‐learning approach

Journal of Arrhythmia, 2021
Background Patients with atrial fibrillation (AF) usually have a heterogeneous co‐morbid history, with dynamic changes in risk factors impacting on multiple adverse outcomes.
Gregory Y. H. Lip, George Tran, Ash Genaidy, Patricia Marroquin, Cara Estes   +4 more
doaj   +1 more source

Historical and textual analysis of the drafts of the new national anthem of the USSR of 1955–1956

Вестник Самарского университета: История, педагогика, филология, 2022
The relevance of this topic is that on the basis of a wide range of archival sources, the work of a special commission under the leadership of D.T. Shepilov, which was created by the decision of the Presidium of the Central Committee of the CPSU at the ...
G. E. Kozlovskaya, A. P. Artyukov, G. D. Drobinin   +2 more
doaj   +1 more source

National Symbols and Marks in Textbooks on Nature and Society of the First Education Cycle of the Countries of the Western Balkan

Društvene i Humanističke Studije, 2023
The paper presents the results of research conducted with the aim of determining the contribution of textbooks on nature and society of the first cycle of education in the countries of the Western Balkans to the formation of the concept of national ...
Danijela Vasilijević, Hadži Živorad Milenović, Biljana Alavanja   +2 more
doaj   +1 more source