Results 1 to 10 of about 41,289 (63)

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 23, September 8, 2025.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail   +3 more
wiley   +1 more source

Immunity Switches and Macrophage Manipulations: Trauma, Ovulation, and Depression as Latent Tuberculosis Reactivation Risks

open access: yesAmerican Journal of Human Biology, Volume 37, Issue 9, September 2025.
ABSTRACT Inflammation is the immune system's natural response to initial tuberculosis infection. Tuberculosis bacteria have gained adaptations to manipulate the inflammatory process, sometimes settling into latency and containment in granulomas, ensuring their survival.
Stacie Burke
wiley   +1 more source

Rapid Sequence Identification of Potential Pathogens Using Techniques from Sparse Linear Algebra

open access: yes, 2015
The decreasing costs and increasing speed and accuracy of DNA sample collection, preparation, and sequencing has rapidly produced an enormous volume of genetic data. However, fast and accurate analysis of the samples remains a bottleneck. Here we present
Chiu, Nelson   +4 more
core   +1 more source

A case of septicaemic anthrax in an intravenous drug user [PDF]

open access: yes, 2011
<p><b>Background:</b> In 2000, Ringertz et al described the first case of systemic anthrax caused by injecting heroin contaminated with anthrax.
AM Friedlander   +23 more
core   +2 more sources

A comprehensive analysis of the relationship between inflammasomes and autophagy in human tumors: Recent developments

open access: yesJournal of Cell Communication and Signaling, Volume 19, Issue 3, September 2025.
The interaction between inflammasomes and autophagy is crucial for maintaining the balance between necessary immune responses and the avoidance of excessive inflammation. Autophagy can inhibit the activation of the NLRP3 inflammasome by degrading endogenous activators, such as damaged mitochondria that produce reactive oxygen species (ROS), as well as ...
Sai Liu, Jingzhou Zhang
wiley   +1 more source

Ready or Not? Protecting the Public's Health From Diseases, Disasters, and Bioterrorism, 2011 [PDF]

open access: yes, 2011
Highlights examples of preparedness programs and capacities at risk of federal budget cuts or elimination, examines state and local public health budget cuts, reviews ten years of progress and shortfalls, and outlines policy issues and ...

core  

Fully integrated digital microfluidics platform for automated immunoassay; a versatile tool for rapid, specific detection of a wide range of pathogens [PDF]

open access: yes, 2019
© 2018 Elsevier Ltd. All rights reserved. This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Licence http://creativecommons.org/licenses/by-nc-nd/4.0/.With the tangible threat posed by the ...
Coudron, Loic   +6 more
core   +2 more sources

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. [PDF]

open access: yes, 2010
Francisella tularensis, the causative agent of tularemia, infects host macrophages, which triggers production of the proinflammatory cytokines interleukin 1beta (IL-1beta) and IL-18. We elucidate here how host macrophages recognize F.
Alnemri, Emad S   +12 more
core   +3 more sources

The Hennepin Healthcare Forced Ketamine Studies, Excited Delirium, and Police Violence

open access: yesHastings Center Report, Volume 55, Issue 5, Page 29-40, September–October 2025.
Abstract In the summer of 2018, the Minneapolis Star Tribune reported clinical trials at Hennepin County Medical Center in which emergency medical personnel were injecting agitated individuals with ketamine, often at the urging of police. These individuals were enrolled in the trials without their knowledge or consent.
Carl Elliott, Lauren Wilson
wiley   +1 more source

Ready or Not? Protecting the Public's Health in the Age of Bioterrorism, 2004 [PDF]

open access: yes, 2004
Examines ten key indicators to evaluate state preparedness to respond to bioterrorist attacks and other public health emergencies.
Laura M. Segal   +3 more
core  

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