Results 161 to 170 of about 1,237,816 (284)

The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis

open access: yesAllergy, EarlyView.
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith   +9 more
wiley   +1 more source

In Vivo Comparison of Algorithms Estimating Left Ventricular Stroke Work From LVAD‐Derived Pump Parameters

open access: yesArtificial Organs, EarlyView.
Our study validates non‐invasive stroke work estimation algorithms derived from LVAD pump parameters across preload reduction (inferior vena cava occlusion), afterload increase (aorta descendens occlusion), contractility increase (dobutamine infusion), and LVAD speed ramp interventions in 22 pigs.
Moriz A. Habigt   +7 more
wiley   +1 more source

The Welfarist Consequentialist Case Against Conscientious Objection in Healthcare: Empirical Failures, Normative Confusions, and the Primacy of Patient Care

open access: yesBioethics, EarlyView.
ABSTRACT We have defended the view that there should be no accommodation of conscientious objectors in health care. Numerous critics have advanced arguments designed to defeat this conclusion. We respond here to what we take to be the most serious of the criticisms directed at our analysis. We begin with two distinct consequentialist lines.
J. Savulescu, U. Schuklenk
wiley   +1 more source

Algorithmic Bioethics: A Defense and Demonstration

open access: yesBioethics, EarlyView.
ABSTRACT In this paper, we argue for the adoption of algorithmic bioethics, which uses algorithms, in the form of decision trees, to articulate, understand, apply, and evaluate bioethical arguments. Algorithms bring many benefits to the study of bioethics: they clearly, precisely, and transparently articulate the decision procedure and facts relevant ...
Shang Long Yeo   +3 more
wiley   +1 more source

LLM‐based prior elicitation for Bayesian graphical modeling

open access: yesBritish Journal of Mathematical and Statistical Psychology, EarlyView.
ABSTRACT In the Bayesian graphical modeling framework, priors on network structure encode theoretical assumptions and uncertainty about the topology of psychological constructs under study. For instance, the Bernoulli prior specifies the probability of each pairwise interaction, the Beta–Bernoulli prior governs expected network density, and the ...
Nikola Sekulovski   +2 more
wiley   +1 more source

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