Results 121 to 130 of about 113,269 (263)

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

open access: yesiMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo   +4 more
wiley   +1 more source

A gut microbiome‐lipid axis in early pregnancy is associated with metabolic dysregulation and diabetes risk

open access: yesiMeta, EarlyView.
Early‐pregnancy microbiome and lipidome profiling identified a microbiome‐glycosphingolipid axis associated with later gestational diabetes mellitus (GDM) risk. In the prospective pregnancy cohort, women who later developed GDM showed altered gut microbial composition, enriched microbial lipid biosynthesis pathways, and broad plasma lipidomic changes ...
Zhonghan Sun   +18 more
wiley   +1 more source

Evaluation of liver stiffness measurement–based scores in liver transplantation recipients

open access: yesLiver Transplantation, EarlyView., 2022
Abstract Combining bioclinical parameters with liver stiffness measurement (LSM) has improved the diagnostic performance of vibration‐controlled transient elastography (VCTE) for detection of advanced fibrosis in patients with chronic liver disease. However, this approach has not yet been tested in liver transplantation (LT) recipients.
Tamoore Arshad   +11 more
wiley   +1 more source

Body, Emotions, and Hormones: A Systematic Review of Body Dissatisfaction, Emotion Regulation, and Puberty in Adolescence

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Objective Body dissatisfaction often arises from a discrepancy between perceived and ideal body images, posing a risk for psychological issues like depression and eating pathologies, particularly during adolescence. Puberty's rapid physical changes may exacerbate the feeling of dissatisfaction, additionally pubertal changes also influence ...
Isabella Muscolino   +3 more
wiley   +1 more source

Human Health Risk Assessment From Exposure to Toxic Metals in Soils and Leafy Vegetables in Smallholder Farms of Northeastern Brazil

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT This study assessed human health risks associated with exposure to potentially toxic metals (PTMs) in soils and leafy vegetables cultivated in smallholder agricultural systems in Northeastern Brazil. Soil and vegetable samples were collected from 18 agricultural areas and analyzed for cadmium (Cd), chromium (Cr), copper (Cu), iron (Fe), nickel
Fernando Ferreira da Cunha Filho   +5 more
wiley   +1 more source

Associations between anthropometric measures and cardiovascular risk biomarkers in women with short stature. [PDF]

open access: yesJRSM Cardiovasc Dis
Britto RPA   +8 more
europepmc   +1 more source

Glycemic Regulation and Renal Function by Heavy Metal Exposure: A Cross‐Sectional Analysis on Cement Plant Workers

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Heavy metal exposure is known to have various effects on renal function and blood glucose regulation. The main objective of this study was to evaluate the effects of cement dust and some metal (cadmium, manganese, nickel, and zinc) exposure on blood glucose and renal function parameters in male cement plant workers.
Duygu Seyhan Erdoğan   +5 more
wiley   +1 more source

The Role of Serum Uric Acid in the Prediction of Type 2 Diabetes Mellitus: Tehran Lipid and Glucose Study

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study aimed to examine the association between serum uric acid and incident type 2 diabetes mellitus. The study included 5719 subjects (2588 men) aged ≥ 30 years without T2DM at baseline. Multivariate Cox proportional hazard analyses were applied using SUA as continuous and categorical variables. Subjects followed up during a median follow‐up of 8.
Nahid Kord   +5 more
wiley   +1 more source

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