Results 61 to 70 of about 108,228 (267)

The risk of chronic kidney disease in relation to anthropometric measures of obesity: A Swedish cohort study

open access: yesBMC Nephrology, 2021
Background It has been shown that individuals with obesity have a higher risk for chronic kidney disease (CKD). However, it is unclear which measure of obesity is most useful for prediction of CKD in the general population.
Ensieh Memarian   +4 more
doaj   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti   +9 more
wiley   +1 more source

Mechanism‐informed machine learning for individualized tacrolimus dose adjustment in the early post‐kidney transplant period

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus dosing in the early post‐kidney transplant period is challenging due to a narrow therapeutic index and substantial interindividual pharmacokinetic (PK) variability. This study aimed to develop and validate mechanism‐informed machine learning (ML) models to support individualized tacrolimus dosing during this critical period ...
Hui Yu   +4 more
wiley   +1 more source

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić   +8 more
wiley   +1 more source

Controlling the Field: Memory, Labor, and Ethics in Oral Histories of Brazilian Human Genetics

open access: yesBerichte zur Wissenschaftsgeschichte, EarlyView.
This article examines how oral histories of twentieth‐century human genetics in Brazil reveal the politics of memory of fieldwork. Through a comparative analysis of interviews with prominent geneticist Francisco M. Salzano and technician Girley V. Simões, who worked with him for most of his career, this study explores the narrative strategies each ...
Rosanna Dent   +1 more
wiley   +1 more source

Frailty and Cardiovascular Events as Determined by Body Composition: A Systematic Review

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Frailty phenotypes and risk of cardiovascular disease. Sarcopenic obese phenotype is associated with increased prevalence of cardiovascular risk factors and progression of metabolic syndrome, leading to cardiovascular events and cardiovascular mortality, while the Anorexic malnourished phenotype is associated with reduced prevalence of cardiovascular ...
Ishleen Oberoi   +5 more
wiley   +1 more source

Neurofeedback for Binge‐Eating Disorder: Neurophysiological Outcome Predictors and Rapid Response

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Pioneer studies suggested the effectiveness of food‐specific electroencephalography (EEG) and real‐time functional near‐infrared spectroscopy (rtfNIRS) neurofeedback (NF) trainings in the treatment of binge‐eating disorder (BED). These trainings aim to improve participants' neurophysiological self‐regulation.
Ben Schreglmann   +3 more
wiley   +1 more source

Intensive Multidisciplinary Intervention for Young Children With ARFID: Clinical Outcomes and Parental Experiences From a Prospective Cohort Study

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective To assess clinical outcomes and parental experiences following an intensive multidisciplinary intervention (IMI) for children with Avoidant Restrictive Food Intake Disorder (ARFID). Method A prospective cohort of 28 children (aged 2–8 years) with severe eating difficulties, all meeting ARFID diagnostic criteria at baseline ...
Helena Holmäng   +7 more
wiley   +1 more source

Adherence to Healthy Lifestyle among Hypertensive Patients and Its Association with Anthropometric Measures

open access: yesآموزش بهداشت و ارتقاء سلامت ایران, 2015
Background and objective: The risk of coronary heart diseases is highly associated with our lifestyle. To reduce or prevent diseases including coronary, diabetes and many types of cancers we need to adhere to proper lifestyle which seems not to be easily
Zahra Sedaghat   +2 more
doaj  

Testing the Motor Competence and Health-Related Variable Conceptual Model: A Path Analysis

open access: yesJournal of Functional Morphology and Kinesiology, 2018
The purpose of this study was to empirically test a comprehensive conceptual model linking gross motor skills, school day physical activity and health-related variables in a sample of sixth graders.
Ryan Donald Burns, You Fu
doaj   +1 more source

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