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Novel Delivery Systems for Anti-Allergic Agents: Allergic Disease and Innovative Treatments

open access: yesCurrent Drug Delivery, 2015
Anti-allergic agents are used to treat a great variety of diseases which usually involve an inflammation reaction. These compounds act by inhibiting the release and the effects of inflammatory mediators (e.g. histamine) in the target tissue. The purpose of anti-allergy therapy is to deliver the drug to its local of action in a therapeutic concentration,
Lopes, Carla Martins   +2 more
openaire   +4 more sources
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Recent Advances in the Development of Anti-allergic Drugs [PDF]

open access: yesAllergology International, 2006
Research over the past decade has provided information concerning the onset and treatment of allergic diseases, including bronchial asthma, allergic rhinitis and atopic dermatitis.
Hitomi Teramachi
exaly   +2 more sources

The effect of the anti-allergic agent avil on abnormal scar fibroblasts

Burns, 1999
Abnormal wound healing in humans leads to the formation of hypertrophic scar and keloids. These abnormal scars accumulate excessive extracellular matrix proteins through increased synthesis as well as decreased degradation. In order to find a therapeutic control for scar formation, we investigated the effect of avil (pheniramine maleate) on fibroblasts
J, Venugopal   +3 more
openaire   +2 more sources

P2X7 receptor antagonist activity of the anti-allergic agent oxatomide

European Journal of Pharmacology, 2015
Activation of the P2X7 receptor by extracellular ATP is associated with various immune responses including allergic inflammation. Anti-allergic agents, such as H1-antihistamines, are known to inhibit the effects of different chemical mediators such as acetylcholine and platelet-activating factor.
Kazuki, Yoshida   +2 more
openaire   +2 more sources

Clinical investigation of agents with prophylactic anti‐allergic effects in bronchial asthma*

Clinical & Experimental Allergy, 1978
SummaryTo determine the efficacy of ketotifen as an oral anti‐asthmatic agent, experimental and therapeutic long‐term trials were carried out. Four models were used in the experimental therapeutic trials and the antihislaminic agent clemastine and disodium cromoglycate were used as comparative substances.
L, Craps, C, Greenwood, P, Radielovic
openaire   +2 more sources

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