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Novel Delivery Systems for Anti-Allergic Agents: Allergic Disease and Innovative Treatments
Current Drug Delivery, 2015 Anti-allergic agents are used to treat a great variety of diseases which usually involve an inflammation reaction. These compounds act by inhibiting the release and the effects of inflammatory mediators (e.g. histamine) in the target tissue. The purpose of anti-allergy therapy is to deliver the drug to its local of action in a therapeutic concentration,
Carla M. Lopes
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P2X7 Receptor Antagonist Activity of the Anti-Allergic Agent Oxatomide
European Journal of Pharmacology, 2015Activation of the P2X7 receptor by extracellular ATP is associated with various immune responses including allergic inflammation. Anti-allergic agents, such as H1-antihistamines, are known to inhibit the effects of different chemical mediators such as acetylcholine and platelet-activating factor.
Kazuki Yoshida +2 more
exaly +3 more sources
The effect of the anti-allergic agent avil on abnormal scar fibroblasts
Burns, 1999Abnormal wound healing in humans leads to the formation of hypertrophic scar and keloids. These abnormal scars accumulate excessive extracellular matrix proteins through increased synthesis as well as decreased degradation. In order to find a therapeutic control for scar formation, we investigated the effect of avil (pheniramine maleate) on fibroblasts
J, Venugopal +3 more
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Clinical investigation of agents with prophylactic anti‐allergic effects in bronchial asthma*
Clinical & Experimental Allergy, 1978SummaryTo determine the efficacy of ketotifen as an oral anti‐asthmatic agent, experimental and therapeutic long‐term trials were carried out. Four models were used in the experimental therapeutic trials and the antihislaminic agent clemastine and disodium cromoglycate were used as comparative substances.
L, Craps, C, Greenwood, P, Radielovic
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[Anti-allergic properties of pipethiaden--a new preventive agent for migraine].
Ceskoslovenska farmacie, 1989Pipethiadene, a prophylactic of vasomotoric headaches of the series of 4,9-dihydrothieno(2,3-c)-2-benzothiepine derivatives, shows a peripheralpharmacological profile of an antiallergic agent. The experiments in rats showed a high antianaphylactic effect of pipethiadene in the passive cutaneous anaphylaxis (PCA) test.
H, Frycová, J, Metys
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