Results 21 to 30 of about 84,389 (260)

Screening of Bioactive Fraction of Radix Paeoniae Alba and Enhancing Anti-Allergic Asthma by Stir-Frying Through Regulating PI3K/AKT Signaling Pathway

Frontiers in Pharmacology, 2022
Allergic asthma is a common respiratory inflammation disease. The crude Radix Paeoniae Alba (RPA) and its processed products have been used frequently as antipyretic and anti-inflammatory agents in traditional medicine.
Xia’nan Sang, Jialiang Ying, Xuedong Wan, Xin Han, Qiyuan Shan, Qiang Lyu, Qiao Yang, Kuilong Wang, Min Hao, Erlong Liu, Gang Cao   +10 more
doaj   +1 more source

Executive summary: Japanese guidelines for allergic rhinitis 2020

Allergology International, 2023
The Practical Guideline for the Management of Allergic Rhinitis, the fist guideline for allergic rhinitis in Japan, was prepared after a symposium held by the Japanese Society of Allergology in 1993.
Mitsuhiro Okano, Shigeharu Fujieda, Minoru Gotoh, Yuichi Kurono, Atsushi Matsubara, Nobuo Ohta, Atsushi Kamijo, Takechiyo Yamada, Yuji Nakamaru, Mikiya Asako, Daiju Sakurai, Tetsuya Terada, Shuji Yonekura, Masafumi Sakashita, Kimihiro Okubo   +14 more
doaj   +1 more source

Biological therapy in severe asthma: A gem or a jam

The Egyptian Journal of Bronchology, 2016
Severe asthma remain a great challenge for physicians. Several therapies are suggested. The only one proved to be effective in severe allergic asthma is Omalizumab. Other biological agents are in different phases in research, yet, only few of them proved
Hesham Raafat
doaj   +1 more source

Usefulness of Suplatast Tosilate in Patients with Mild Bronchial Asthma —Comparison with Beclomethasone Dipropionate

Allergology International, 2005
Background: Suplatast tosilate is a type 2 (Th2) cytokine inhibitor that blocks the production of IgE antibodies and the invasion of tissues by eosinophils during an allergic reaction.
Takahiko Horiguchi, Rieko Kondo, Junichi Miyazaki, Mamoru Shiga, Masahiro Hirose, Tomohiro Ito, Koji Fukumoto, Hiroshi Torigoe, Soichi Tachikawa   +8 more
doaj   +1 more source

Drug Allergy in Adults at a Multidisciplinary Hospital: Prevalence Assessment Using the Global Trigger Tool

Безопасность и риск фармакотерапии
INTRODUCTION. Allergic drug reactions in hospitalised patients limit the opportunities for rational pharmacotherapy and increase the risk of polypharmacy due to the need for managing the patient’s condition and prescribing anti-allergic agents.
V. R. Koval, O. I. Butranova, T. G. Konstantinova, A.Q.S. Al-Mayahi   +3 more
doaj   +1 more source

Synthesis and properties of novel alkoxy- and phenoxyalkyl ethers of secondary and tertiary ethynylpiperidin-4-ols possessing unusual analgesic, anti-bacterial, anti-spasmotic, and anti-allergic properties as well as low toxicity

Journal of Saudi Chemical Society, 2009
Methodology was developed to obtain a series of unusual alkoxy- and phenoxyalkyl ethers of secondary and tertiary ethynylpiperidin-4-ols representative examples of which were evaluated for analgesic, anti-bacterial, anti-spasmotic, and anti-allergic ...
Valentina K. Yu, Aissulu Zh. Kabdraissova, Kaldybay D. Praliyev, Svetlana N. Shin, K. Darrell Berlin   +4 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source