Results 121 to 130 of about 7,565,652 (283)

Antimicrobial Responses to Bacterial Metabolic Activity and Biofilm Formation Studied Using Microbial Fuel Cell-Based Biosensors

Biosensors
Simultaneous monitoring of antimicrobial responses to bacterial metabolic activity and biofilm formation is critical for efficient screening of new anti-biofilm drugs.
Wenguo Wu, Huiya Hong, Jia Lin, Dayun Yang   +3 more
doaj   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

Hyaluronidase involvement in Streptococcus pneumoniae biofilm activity [PDF]

Streptococcus pneumoniae causes numerous severe infections and results in a significant number of mortality cases due to various virulence factors, including its ability to form a biofilm.
Enche Othman, Mohammad Izwan, Mohd Amin, Nor Munirah, Mohd Nayian, Nurul Azahana, Ahmad Suaidan, Muhammad Abdullah, Abu Mansor, Abu Zarrin, Ahmad Yusof @ Hanafi, Hanani   +5 more
core   +1 more source

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

Advanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang, Jinwei Li, Shan Hua, Shengming Wu, Chenlong He, Yuan Zhu, Ming Yin, Han Zhou, Huawei Liu, Chika Hasegawa, Jun Lyu, Keyue Xiao, Hua Jiang, Yilong Wang, Yuxin Qian   +14 more
wiley   +1 more source

Environmental and genetic factors influencing biofilm structure

, 2000
It is increasingly evident that biofilms growing in a diverse range of medical, industrial, and natural environments form a similarly diverse range of complex structures (Stoodley et al., 1999a).
Lappin-Scott, H.M., Jorgensen, F., Boyle, J.D., Stoodley, P., Hall-Stoodley, Luanne   +4 more
core   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source

TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis

Advanced Science, EarlyView.
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu, Tiancheng Li, Yu Jin, Yixin Li, Qicheng Liu, Runzhe Fang, Luyao Qu, Xinyue Tang, Ruomei Li, Xiaoyue Zhao, Jin Hao, Bing Fang, Lunguo Xia   +12 more
wiley   +1 more source

Varronia curassavica Jarq. Essential Oils Inhibit the Formation of the Biofilm of Xanthomonas campestris pv. campestris in vitro.

Brazilian Archives of Biology and Technology
The aim of this study was to investigate the anti-biofilm activity of two essential oils from Varronia curassavica Jaq. Two genotypes (VCUR-202 and VCUR-302), previously identified as exhibiting high antimicrobial activity against Xanthomonas campestris,
Rafael Salomão da Silva, Mayara Mendes Gonçalves de Oliveira, Nikolas Emanuel Chaves-Silva, Silmara Caldas Santos, Viviane Talamini, Euler Araujo dos Santos, Arie Fitzgerald Blank, Roberta Pereira Miranda Fernandes   +7 more
doaj   +1 more source

Antimicrobial activity of nitrochalcone and pentyl caffeate against hospital pathogens results in decreased microbial adhesion and biofilm formation

, 2019
The present study investigated the antimicrobial, anti-adhesion and anti-biofilm activity of the modified synthetic molecules nitrochalcone (NC-E05) and pentyl caffeate (C5) against microorganisms which have a high incidence in hospital-acquired ...
Rocha Garcia, Mayara Aparecida [UNESP], Alencar, Severino Matias de, Paganini, Eder Ramos [UNESP], Rosalen, Pedro Luiz, Orlandi Sardi, Janaina de Cassia, Regasini, Luis Octavio, Almeida Sayao de Emeri, Fernanda Teresinha de, de Alencar, Severino Matias, Nazare, Ana Carolina [UNESP], Rocha Garcia, Mayara Aparecida, Nazare, Ana Carolina, Paganini, Eder Ramos, de Almeida Sayao de Emeri, Fernanda Teresinha, Lazarini, Josy Goldoni, Regasini, Luis Octavio [UNESP]   +14 more
core   +1 more source