Results 31 to 40 of about 80,958 (253)

Structure-based minimization of a high-mobility group protein B1 (HMGB1) B box peptide uncouples anti-NETotic activity and anti-biofilm function

Frontiers in Immunology
IntroductionWe previously showed that human HMGB1 has anti-biofilm activity localized to a 97-amino-acid B-Box-derived peptide (mB Box-97), engineered with a C106S mutation to reduce HMGB1’s proinflammatory properties while retaining anti-biofilm ...
Kunal R. More, Jaime D. Rhodes, Lauren O. Bakaletz, Lauren O. Bakaletz, Steven D. Goodman, Steven D. Goodman   +5 more
doaj   +1 more source

Anti-biofilm Activities from Resveratrol against Fusobacterium nucleatum [PDF]

Frontiers in Microbiology, 2016
Fusobacterium nucleatum is a Gram-negative, anaerobic bacterium that plays an important role in dental plaque biofilm formation. In this study, we evaluate the effect of resveratrol, a phytoalexin compound, on F. nucleatum biofilm formation. The effects of different concentrations of resveratrol on biofilms formed on 96-well microtiter plates at ...
He, Zhiyan, Huang, Zhengwei, Zhou, Wei, Tang, Zisheng, Ma, Rui, Liang, Jingping   +5 more
openaire   +2 more sources

Synthesis, antimicrobial, anti-biofilm evaluation, and molecular modelling study of new chalcone linked amines derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
A series of amide chalcones conjugated with different secondary amines were synthesised and characterised by different spectroscopic techniques 1H NMR, 13C NMR, and ESI-MS. They were screened for in vitro antibacterial activity. Compounds 36, 37, 38, 42,
Shahenda M. El-Messery, El-Sayed E. Habib, Sarah T. A. Al-Rashood, Ghada S. Hassan   +3 more
doaj   +1 more source

Antifungal and anti-biofilm activity of designed derivatives from kyotorphin

Fungal Biology, 2020
Kyotorphin (KTP, l-tyrosyl-l-arginine) is an endogenous analgesic neuropeptide first isolated from bovine brain in 1979. Previous studies have shown that kyotorphins possess anti-inflammatory and antimicrobial activity. Six kyotorphins-KTP-NH2, KTP-NH2-DL, ibuprofen-conjugated KTP (IbKTP), IbKTP-NH2, N-methyl-D-Tyr-L-Arg, and N-methyl-L-Tyr-D-Arg-were ...
Martins de Andrade, Vitor, Bardají, Eduard, Heras, Montserrat, Ramu, Vasanthakumar G., Junqueira, Juliana Campos, Diane dos Santos, Jéssica, Castanho, Miguel A. R. B., Conceição, Katia   +7 more
openaire   +5 more sources

Determination of stability and kinetic characterization of lysozyme (isolated from Bacillus subtilis BSN314)

The Microbe
This study investigated the stability and anti-biofilm activity of a lysozyme purified from Bacillus subtilis BSN314. The hypothesis that the enzyme's anti-biofilm effect is concentration- and time-dependent was tested. Lysozyme stability was assessed by
Muhammad Naveed, Sai Wen, Anas Sajjad, Binbin Si, Malik Wajid Hussain Chan, Fenghuan Wang   +5 more
doaj   +1 more source

The Activity of Cotinus coggygria Scop. Leaves on Staphylococcus aureus Strains in Planktonic and Biofilm Growth Forms

Molecules, 2015
The purpose of this study was to detect the effectiveness of Cotinus coggygria Scop. leaves methanol extract against planktonic and biofilm growth forms of Staphylococcus aureus.
Katarína Rendeková, Silvia Fialová, Lucia Jánošová, Pavel Mučaji, Lívia Slobodníková   +4 more
doaj   +1 more source

The anti-biofilm activity of hydrogen peroxide against Escherichia coli strain FL-Tbz isolated from a pharmaceutical water system

Journal of Water and Health, 2022
Biofilms are considered a significant reason for the failure of disinfection strategies in industrial water systems due to their resistance to antimicrobial agents.
Afsaneh Farjami, Sina Jalilzadeh, Mohammadreza Siahi-Shadbad, Farzaneh Lotfipour   +3 more
doaj   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

TRACING THE ANTIBACTERIAL, ANTIFUNGAL AND ANTI-BIOFILM ACTIVITIES OF ROOT EXTRACT BAJAKAH TAMPALA (SPATHOLOBUS LITTORALIS HASSK)

Jurnal Farmasi Sains dan Praktis
Biofilm is a common causative factor for urinary tract infections due to catheter usage with a percentage of infection around 70-80%. The Bajakah tampala (Spatholobus littoralis Hassk) is one of native plants of Kalimantan which contains phenolic ...
Endang Setyowati, Elza Fadia Irzani, Chaerul Fadly Mochtar Luthfi, Hasyrul Hamzah   +3 more
doaj   +1 more source