Results 211 to 220 of about 4,077,341 (314)

Evaluation of cardiac histology and cell death markers during the progression of diabetes in a streptozotocin‐induced diabetes rat model

Animal Models and Experimental Medicine, EarlyView.
Daily insulin administration in streptozotocin‐induced diabetic rats prevented cardiac damage associated with diabetic cardiomyopathy, including hypertrophy, fibrosis, and expression of cell death markers, at 12 weeks. However, cyclophilin D, a marker of mitochondrial permeability transition pore‐opening‐associated cell death (necrosis), was observed ...
Tamara Sáez, Ivo Carrasco‐Wong, Juan Varas, Sebastián San Martín, Jaime A. Riquelme, Rienzi Díaz‐Navarro   +5 more
wiley   +1 more source

Decoding Carbon Dot Purity by Nuclear Magnetic Resonance

Angewandte Chemie, EarlyView.
NMR spectroscopy tracks the removal of molecular and oligomeric impurities in carbon dots, enabling a (semi)quantitative evaluation of their purity through integrated peak analysis. ABSTRACT Carbon dots (CDs) have attracted increasing attention in recent years and have been widely explored in many fields.
Yalei Hu, Alberto Bianco
wiley   +2 more sources

Vitamin A Derivatives and Adipose Tissue Differentiation: Molecular Pathways Driving Browning and Anti-Obesity Effects. [PDF]

Curr Obes Rep
Bilikozen Aygun B, Basturk B, Ayaz A.
europepmc   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Potential role of postbiotics in supporting lean mass preservation and weight-loss sustainability during GLP-1-based anti-obesity therapy. [PDF]

Front Nutr
Cengiz Kaynakcı E.
europepmc   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source

Disease-associated adipose browning: current evidence and perspectives. [PDF]

Adipocyte
Zhang X, Han X, Xu J, Li G.
europepmc   +1 more source

High-intensity intermittent training promotes adipose tissue browning via the IL-27/p38 MAPK-PGC-1α signaling pathway in diet-induced obese rats. [PDF]

Front Physiol
Wang C, Hu Y, Chen J, Wu Y.
europepmc   +1 more source

Advances in Nano-Phototherapy for Targeted Fat Reduction: From Mechanisms to Clinical Translation in Obesity. [PDF]

Int J Nanomedicine
Zhang Y, Qian W, Zhang X, Gao X, Wei Y, Ding J, Zhao H.   +6 more
europepmc   +1 more source

Nobiletin Attenuates Adipogenesis and Promotes Browning in 3T3-L1 Adipocytes Through Exosomal miRNA-Mediated AMPK Activation. [PDF]

Curr Issues Mol Biol
Chauhan S, Baek H, Jaiswal V, Park M, Lee HJ.   +4 more
europepmc   +1 more source