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Anti-Cancer Biosurfactants

2021
Biosurfactants produced by different types of microorganisms are amphiphilic biomolecules with active surface properties. Recently, biosurfactants have emerged as promising agents for cancer therapy since a high diversity of these molecules has shown the ability to induce cytotoxicity against many cancer cell lines, thus regulating cancer progression ...
Magalhães, Flávia F.   +6 more
openaire   +2 more sources

Anti-cancer radiopharmaceuticals

Anti-Cancer Drugs, 1991
Therapeutic nuclear medicine is rapidly developing as an additional treatment modality in oncology. A great variety of specific tumor-seeking radiopharmaceuticals is applied both for diagnostic scintigraphy and treatment, using multiple routes and mechanisms to target radionuclides at tumors.
openaire   +2 more sources

Hsp90 as an anti-cancer target

Drug Resistance Updates, 1999
Heat shock protein 90 is one of the most abundant cellular proteins. Although its functions are still being characterized, it appears to serve as a chaperone for a growing list of cell signaling proteins, including many tyrosine and serine/threonine kinases, involved in cell proliferation and/or survival.
Len, Neckers   +2 more
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Mutagenicity of anti-cancer nitrobenzofuroxans

Mutation Research, 1977
Anti-leukaemically active benzofuroxans were tested for mutagenicity in Salmonella typhimurium. Mutagenicity was not found to be correlated to the previously established anti-leukaemic activity. One anti-leukaemically inactive compound after exposure to liver microsomal enzymes proved the most mutagenic of the derivatives for TA100, whereas after ...
S, Thompson, L, Kellicutt
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The microbiome in anti-cancer therapy

Seminars in Immunology, 2017
The commensal microbiome constitutes an important modulator of host physiology and risk of disease, including cancer development and progression. Lately, the microbiome has been suggested to modulate the efficacy of anti-cancer treatment. Examples include chemotherapy and total body irradiation-induced barrier function disruption, leading to microbial ...
Stavros, Bashiardes   +3 more
openaire   +2 more sources

microRNAs as Anti-Cancer Therapy

Current Pharmaceutical Design, 2014
MicroRNAs (miRNAs) are endogenously expressed and evolutionarily conserved small non-coding RNAs, which regulate gene expression. Several studies have shown that they are involved in fundamental biological processes, such as proliferation and apoptosis.
Michela, Garofalo   +2 more
openaire   +2 more sources

Interferon: An anti-cancer agent?

Cancer Treatment Reviews, 1979
Summary The last 12 months have seen a tremendous resurgence of interest in IF, stimulated in part by the initial clinical reports of tumour regression and also by the prospect that production problems are finally being overcome and increased supplies of material may be available in the near future.
openaire   +2 more sources

Targeting cancer-promoting inflammation — have anti-inflammatory therapies come of age?

Nature Reviews Clinical Oncology, 2021
Michael Karin   +2 more
exaly  

Resistance Mechanisms to Anti-PD Cancer Immunotherapy

Annual Review of Immunology, 2022
Matthew Vesely, Lieping Chen
exaly  

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