Results 71 to 80 of about 6,599,962 (291)
Expert consensus of 177Lu-labeled PSMA radioligand therapy for clinical practice of prostate cancer (2024 edition) [PDF]
Zhongguo aizheng zazhi177Lu-labeled prostate-specific membrane antigen radioligand therapy (177Lu-PSMA-RLT) is an innovative treatment approach that precisely delivers β radiation emitted by 177Lu to prostate cancer cells, causing radiation damage to the tumor cells’ DNA and ...
Cancer Nuclear Medicine Committee of China Anti-Cancer Association, Chinese Association of Nuclear Medicine Physicians
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
The TRAIL to an anti-cancer agent
Drug Resistance Updates, 1999 ell death receptors such as Fas/APO1/CD95 or the Tumor Necrosis Factor Receptor#1 (TNFR1) are potent inducers of apoptosis once overexpressed or engaged by their respective ligands Fas or Tumor Necrosis Factor (TNF) (see 1 and 2 for review).As systemic agents for cancer therapy, however, Fas and TNF have major limitations that have kept them out of the
openaire +2 more sources
Cancer Trends: Cancer of the liver and biliary tract
, 2010 Liver cancer consists of two main types—hepatocellular carcinoma (HCC) which accounts for about 60% of cases, and intrahepatic bile duct cholangiocarcinoma (ICC), which accounts for about 20%. The liver is one of the less common cancer sites, about 0.
National Cancer Registry Ireland (NCRI)
core
Ganoderma Lucidum Polysaccharides As An Anti-Cancer Agent
, 2018 The mushroom Ganoderma lucidum (G. lucidum) has been used for centuries in Asian countries to treat various diseases and to promote health and longevity. Clinical studies have shown beneficial effects of G.
Sohretoglu, Didem, Huang, Shile
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Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Vascular cell adhesion molecule (VCAM)-1 has garnered significant research attention due to its potential as a disease biomarker and drug target across several inflammatory pathologies—including atherosclerosis, asthma, rheumatoid arthritis, and ...
Ta, Hang Thu +2 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Mucinous cystadenocarcinoma of the breast: the challenge of diagnosing a rare entity
Rare Tumors, 2017 Mucinous cystadenocarcinoma is an extremely rare variant of primary breast tumor which is histologically similar to mucinous cystadenocarcinoma of the ovary and pancreas. Herein we report a case of a 63 years old woman diagnosed with diverse histological
Nektarios Koufopoulos +4 more
doaj +1 more source