Anti-Emetics in Children Receiving Chemotherapy for Solid Tumors and Leukemia: Pharmacology and Optimization of Therapy for Nausea and Vomiting [PDF]
PharmaceuticalsThe management of chemotherapy-induced nausea and vomiting (CINV) in children remains challenging due to differences in the chemotherapy regimens, their relative emetogenicity compared to that in adults and differences in drug metabolism and the ...
Shuvadeep Ganguly +3 more
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A History of Drug Discovery for Treatment of Nausea and Vomiting and the Implications for Future Research [PDF]
Frontiers in Pharmacology, 2018 The origins of the major classes of current anti-emetics are examined. Serendipity is a recurrent theme in discovery of their anti-emetic properties and repurposing from one indication to another is a continuing trend.
Gareth J. Sanger, Paul L. R. Andrews
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Reye Syndrome and Anti-Emetics
Pediatric Neurology Briefs, 1991 A drug-induced encephalopathy mainly by anti-emetics in two children with a diagnosis of Reye syndrome is reported from the Department of Paediatrics, University Hospital, Gasthuisberg, Leuven, Belgium.
J Gordon Millichap
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Impact of Preoperative Gum Chewing on Postoperative Anti-Emetic Use in Robot-Assisted Laparoscopic Surgery for Benign Ovarian Masses: A Prospective, Single-Blinded Randomized Controlled Trial [PDF]
MedicinaBackground and Objectives: Postoperative nausea and vomiting (PONV) is a common issue for females undergoing gynecological surgeries, including those assisted by robotic systems. Despite available prophylactic measures, the incidence of PONV remains high,
Min Suk Chae +3 more
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Comparative evaluation of two different doses of nebulized intraperitoneal dexamethasone on postoperative pain in laparoscopic surgeries [PDF]
Journal of Anaesthesiology Clinical PharmacologyBackground and Aims: Postoperative pain is a major cause of discomfort after laparoscopic surgeries and thus necessitates prevention and treatment. This study aims to evaluate and compare two different doses of intraperitoneally nebulized (aerosol size ...
Neha Shrivastava +4 more
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Exploring the effect of differing centre hydration and anti-emetic policies on acute gastrointestinal and renal toxicities in the De-ESCALaTE trial [PDF]
BJC ReportsBackground The De-ESCALaTE trial confirmed the superiority of cisplatin over cetuximab in combination with radiotherapy for the treatment of low risk HPV+ oropharyngeal cancer (HPV + OPC).
Anthony Kong +4 more
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Emesis in Rodents: Present or Absent? A Critical Review of the Evidence and Implications for the Use of Rodents in Biomedical Research [PDF]
BiologyVomiting, a key defence against accidentally ingested toxins, is widely present in mammals. Notably, rodents (e.g., rats, mice) are generally assumed to be unable to vomit, as commonly reported over the last ~100 years, but they are used extensively for ...
Gustavo Alcantara De Sousa +4 more
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Effect of Preoperative Gum Chewing on Postoperative Nausea and Vomiting in Women Undergoing Robotic Laparoscopic Surgery for Uterine Myomas: A Randomized Controlled Trial [PDF]
LifeBackground: Postoperative nausea and vomiting (PONV) remains a frequent and uncomfortable complication in women undergoing robotic gynecological procedures.
Min Suk Chae, Hyun Jung Koh
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Contradictory and weak evidence on the effectiveness of anti-emetics for MTX-intolerance in JIA-patients [PDF]
Pediatric Rheumatology Online Journal, 2018 Casper G. Schoemaker +2 more
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PLoS ONE, 2023 ObjectiveThis study aims to assess the incidence of Emergency Department (ED) visits for benign paroxysmal positional vertigo (BPPV), describe patient characteristics, management practices and predictors of inpatient admission of BPPV patients ...
Jennifer Rizk +4 more
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