Results 251 to 260 of about 7,906 (281)
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Current Medical Research and Opinion, 2000
Nausea and vomiting are common symptoms of migraine, which can be controlled with a variety of anti-emetics including phenothiazines and antihistamines. Metoclopramide and domperidone have an additional prokinetic effect which may be important in migraine to overcome gastric stasis and enhance absorption of oral medication.
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Nausea and vomiting are common symptoms of migraine, which can be controlled with a variety of anti-emetics including phenothiazines and antihistamines. Metoclopramide and domperidone have an additional prokinetic effect which may be important in migraine to overcome gastric stasis and enhance absorption of oral medication.
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Expert Opinion on Investigational Drugs, 2002
Despite important advances in pharmacotherapeutic options for the prevention and treatment of nausea and vomiting during the 1990s, a significant proportion of patients still suffer debilitating nausea and vomiting symptoms. The most problematic areas are chemotherapy-induced nausea and vomiting particularly delayed emesis, postoperative nausea and ...
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Despite important advances in pharmacotherapeutic options for the prevention and treatment of nausea and vomiting during the 1990s, a significant proportion of patients still suffer debilitating nausea and vomiting symptoms. The most problematic areas are chemotherapy-induced nausea and vomiting particularly delayed emesis, postoperative nausea and ...
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Methodology in Anti-Emetic Trials
Oncology, 1992The most promising anti-emetic drugs are identified during preclinical testing. Phase I and II clinical studies are used to optimize doses and schedules for the various routes of administration. Most methodological issues arise in relation to phase III studies.
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Advances in anti-emetic therapy
Cancer Treatment Reviews, 1984Evaluation of the activity of anti-emetic drugs in randomized controlled trials has, in most cases, demonstrated the superiority of treatment over placebo administration for the control of chemotherapy-induced emesis (see Table 15). The degree of control of emesis relates both to the intensity of the emetogenic stimulus and to the effectiveness of the ...
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Guidelines for anti-emetic therapy: acute emesis
European Journal of Cancer, 1999Anti-emetic therapy has become integral to the management of patients with cancer. Goals related to complete emesis control include providing treatment that reduces hospitalisation and time in the ambulatory setting, care that is convenient for the patient and therapy that enhances patients' quality of life.
A A, Fauser +5 more
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Anti-Emetic Principles ofPoria cocos
Planta Medica, 1995The triterpenes isolated from P. cocos and their derivatives were examined for anti-emetic activity. Some of these triterpenes inhibited emetic action induced by oral administration of copper sulfate pentahydrate to leopard frog. The triterpenes having an exomethylene group at C-24 showed anti-emetic activity to frogs.
T, Tai +5 more
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Patients’ willingness to pay for anti‐emetic treatment
Acta Anaesthesiologica Scandinavica, 2006Background: Post‐operative nausea and vomiting (PONV) is a common complication of anaesthesia. This study was conducted in 100 German and 100 Turkish patients scheduled for elective surgery under general anaesthesia to assess the amount patients were willing to pay for an anti‐emetic that completely prevented PONV.Methods: Post‐operatively, using ...
Kerger, H. +6 more
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Prehospital pharmacology: anti-emetics.
EMS magazine, 2008Although there is a paucity of literature on anti-emetic administration in the prehospital setting, paramedic delivery of an appropriate agent according to protocol can decrease the time to treatment for hundreds of thousands of emergency department patients annually who access 9-1-1 and present with nausea and vomiting.
David, Jaslow, Anne, Klimke
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Domperidone - a new anti-emetic.
Drug and therapeutics bulletin, 1983Domperidone (Motilium - Janssen), like metoclopramide (Maxolon, Primperan),1 is a dopamine receptor antagonist. The anti-emetic properties of both drugs are due to two actions: a central one on the chemoreceptor trigger zone (which is functionally outside the blood-brain barrier) and a peripheral action on gastro-intestinal motility and on the lower ...
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Assessing the benefits of anti-emetic innovation
Anti-Cancer Drugs, 1993This paper reviews recent anti-emetic developments, with particular reference to the 5-HT3 receptor antagonists. These drugs are at least as effective as conventional regimens for controlling acute nausea and vomiting in patients receiving highly or moderately emetogenic chemotherapy and abdominal radiotherapy.
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