Results 251 to 260 of about 1,442,499 (293)

Anti-Emetics

open access: yesCurrent Medical Research and Opinion, 2000
Nausea and vomiting are common symptoms of migraine, which can be controlled with a variety of anti-emetics including phenothiazines and antihistamines. Metoclopramide and domperidone have an additional prokinetic effect which may be important in migraine to overcome gastric stasis and enhance absorption of oral medication.
E.A. MacGregor
openaire   +3 more sources

Reye syndrome or side-effects of anti-emetics?

European Journal of Pediatrics, 1991
By analysing two patients initially diagnosed as Reye syndrome evidence is given that in some patients considered as having Reye syndrome, the syndrome is an escalation of symptoms due to viral disease and to unrecognized drug-induced encephalopathy, mainly by anti-emetics.
M Casteels-Van Daele
exaly   +3 more sources

Anti-emetics in development

Expert Opinion on Investigational Drugs, 2002
Despite important advances in pharmacotherapeutic options for the prevention and treatment of nausea and vomiting during the 1990s, a significant proportion of patients still suffer debilitating nausea and vomiting symptoms. The most problematic areas are chemotherapy-induced nausea and vomiting particularly delayed emesis, postoperative nausea and ...
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Advances in anti-emetic therapy

Cancer Treatment Reviews, 1984
Evaluation of the activity of anti-emetic drugs in randomized controlled trials has, in most cases, demonstrated the superiority of treatment over placebo administration for the control of chemotherapy-induced emesis (see Table 15). The degree of control of emesis relates both to the intensity of the emetogenic stimulus and to the effectiveness of the ...
openaire   +2 more sources

Methodology in Anti-Emetic Trials

Oncology, 2009
The most promising anti-emetic drugs are identified during preclinical testing. Phase I and II clinical studies are used to optimize doses and schedules for the various routes of administration. Most methodological issues arise in relation to phase III studies.
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Nausea and the quest for the perfect anti-emetic

European Journal of Pharmacology, 2014
The discovery of anti-emetic agents is reviewed to illustrate the large database (>129,000 papers in PubMed) available for potential data mining and to provide a background to the shift in interest to nausea from vomiting. Research on nausea extends to identification of biomarkers for diagnosis/clinical trials and to understanding why nausea is such a ...
Paul L R, Andrews, Gareth J, Sanger
openaire   +2 more sources

Evaluation of the anti‐emetic action of domperidone

Anaesthesia, 1979
The findings of a study into the anti-emetic properties of domperidone are reported. When the drug was given prophylactically with either morphine or pethidine the study revealed that any anti-emetic property of domperidone was of short duration and that it would not be suitable as a prophylaxis against opiate-induced emesis.
D B, Wilson, J W, Dundee
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Patients’ willingness to pay for anti‐emetic treatment

Acta Anaesthesiologica Scandinavica, 2006
Background:  Post‐operative nausea and vomiting (PONV) is a common complication of anaesthesia. This study was conducted in 100 German and 100 Turkish patients scheduled for elective surgery under general anaesthesia to assess the amount patients were willing to pay for an anti‐emetic that completely prevented PONV.Methods:  Post‐operatively, using ...
Kerger, H.   +6 more
openaire   +2 more sources

Assessing the benefits of anti-emetic innovation

Anti-Cancer Drugs, 1993
This paper reviews recent anti-emetic developments, with particular reference to the 5-HT3 receptor antagonists. These drugs are at least as effective as conventional regimens for controlling acute nausea and vomiting in patients receiving highly or moderately emetogenic chemotherapy and abdominal radiotherapy.
openaire   +2 more sources

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