Results 111 to 120 of about 308 (147)
From Dysplasia to Carcinoma: Expression Patterns of Dermokine, Matriptase, and Tryptase in OPMD
ABSTRACT Background The malignant transformation of oral potentially malignant disorders (OPMDs) lacks reliable molecular markers. Dermokine and matriptase are involved in epithelial differentiation and inflammation, while tryptase is associated with the tumor microenvironment, which may contribute to carcinogenesis.
Lara Maria Alencar Ramos Innocentini +9 more
wiley +1 more source
ABSTRACT Plant immune systems recognise pathogen‐derived molecular patterns to activate defence responses, yet the mechanisms underlying fungal pattern recognition in crops remain largely unclear. Here, we characterise the cysteine‐rich secretory protein SsSCP from the broad‐host‐range fungal pathogen Sclerotinia sclerotiorum as a potent elicitor of ...
Liyuan Zhang +8 more
wiley +1 more source
De Novo Design and Synthesis of Novel Benzoxazinone Derivatives Targeting Dihydroxyacid Dehydratase
ABSTRACT Dihydroxyacid dehydratase (DHAD), a key enzyme in the branched‐chain amino acid (BCAA) synthesis pathway, is a promising herbicide target. Currently, no commercial herbicides target DHAD, and no inhibitors are in development. Structural analysis suggests that coordination with iron–sulfur clusters and hydrophobic interactions with Tyr215 and ...
Bo He +7 more
wiley +1 more source
Domestication‐Selected Promoter Insertion in WRKY17 Increases Cadmium Sensitivity in Apple
ABSTRACT With increasing industrialisation and human activities, heavy metal pollution has become a serious environmental concern, particularly cadmium (Cd) contamination. This study reveals significant differences in Cd tolerance between wild apple (Malus spp.) and cultivated apple (Malus domestica).
Chanyu Wang +15 more
wiley +1 more source
H3K27me3‐Mediated Epigenetic Silencing of FgHMG1 Enables Fungal Host Immune Evasion
ABSTRACT Histone H3 lysine 27 trimethylation (H3K27me3) is essential for fungal pathogenicity, yet its contribution to pathogen–host interactions remains incompletely understood. Here, we profiled H3K27me3 dynamics in Fusarium graminearum during infection and identified 132 H3K27me3‐marked genes (FgHMGs).
Xiaozhen Zhao +17 more
wiley +1 more source
Abstract Over the past decade, large‐scale protests have been pivotal in shaping institutional dynamics and triggering societal change. Despite increased academic attention, the understanding of participants' experiences remains limited. This paper argues for adopting an actor‐centered perspective to gain novel insights into protest dynamics ...
Cristina Pradillo‐Caimari
wiley +1 more source
From Everyman to Hamlet: A Distant Reading
Abstract The sixteenth century sees English drama move from Everyman to Hamlet: from religious to secular subject matter and from personified abstractions to characters bearing proper names. Most modern scholarship has explained this transformation in terms originating in the work of Jacob Burckhardt: concern with religion and a taste for ...
Vladimir Brljak
wiley +1 more source
Citizenship in the Context of Contested Nationalism: Insights From Basque Social Movements
ABSTRACT This paper contributes to knowledge about social movements' visions of citizenship. The aim is twofold: on the one hand, to offer an analysis of how social movements understand the subjective and objective dimensions of citizenship. On the other, to explore how a context of national conflict shapes activists' perspectives on this concept.
Marina Sagastizabal +4 more
wiley +1 more source
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
ABSTRACT The rise in obesity rates in India in the past 3–4 decades is alarming and obesity management needs transformation. A significant barrier is that obesity is often viewed in India as a lifestyle condition rather than a chronic disease, despite broad international recognition of this status.
Sanjay Kalra +11 more
wiley +1 more source

