Results 41 to 50 of about 232,040 (295)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Contra a anti-globalização

open access: yesMeridiano 47, 2017
O presente artigo se pauta em uma critica às posições adotadas pelo movimento anti-globalização.
Paulo Roberto de Almeida
doaj  

The Impossible Mission: Global Justice Movement against Transnational Organized Crime [PDF]

open access: yes, 2012
This article argues that the best counterattack against globally oriented transnational organized crime (TOC) is by a global response. The contribution of participating states and the creation of a collective identity against TOC are both necessary. This
CAYLI, BARIS
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Tática do avestruz

open access: yesMeridiano 47, 2017
A presente análise busca analisar criticamente os efeitos dos novos movimentos sociais, tal como o anti-globalizador e o neoliberal.
Paulo Roberto Almeida
doaj  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Author’s Reply to Wheeler-Getman-Brody Papers [PDF]

open access: yes, 2002
[Excerpt] The contributions of Hoyt Wheeler, Julius Getman and David Brody in the December issue of this journal give important insights into strengths and weaknesses of the Human Rights Watch Report on workers\u27 rights in the United States.
Compa, Lance A
core   +1 more source

Globalizing the Holocaust: A Jewish “Useable Past” in Serbian Nationalism [PDF]

open access: yes, 2005
Contrary to Anthony Smith’s view that national myth-makers derive meaning primarily from a nation’s own positive “useable past”, this article argues that the globalization and universalisation of the Jewish Holocaust has created new poles of identity for
MacDonald, David B
core   +4 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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