Results 51 to 60 of about 10,565 (202)

Reactivation of hepatitis B after liver transplantation: Current knowledge, molecular mechanisms and implications in management [PDF]

, 2018
Chronic hepatitis B (CHB) is a major global health problem affecting an estimated 350 million people with more than 786000 individuals dying annually due to complications, such as cirrhosis, liver failure and hepatocellular carcinoma (HCC).
Chauhan, Ranjit, Gadiparthi, Chiranjeevi, Lahiri, Nivedita, Lingala, Shilpa, Michalak, Tomasz I., Mohanty, Smruti R., Satapathy, Sanjaya K., Wu, Jian   +7 more
core   +2 more sources

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Hepatitis B virus seromarkers among HIV infected adults on ART: An unmet need for HBV screening in eastern Ethiopia.

PLoS ONE, 2019
Progression of chronic HBV to cirrhosis, end-stage liver disease (ESLD), and hepatocellular carcinoma (HCC) is more rapid in HIV positive individuals than those with HBV alone; however, the distribution of HBV seromarkers in HIV infected individuals on ...
Desalegn Admassu Ayana, Andargachew Mulu, Adane Mihret, Berhanu Seyoum, Abraham Aseffa, Rawleigh Howe   +5 more
doaj   +1 more source

Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein [PDF]

, 2014
Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) protein ...
Bert Schepens, Brian Gilbert, Cherrie AH, Connors M, Glezen WP, Kenny Roose, Koen Sedeyn, Liesbeth Vande Ginste, Lieselot Houspie, Marc Van Ranst, Michael Schotsaert, Mills JT, Nicholas JA, Nico Rooijen, Olmsted RA, Pedro Piedra, Sarah De Baets, Ventre K, Walter Fiers, Whitehead SS, Xavier Saelens   +20 more
core   +3 more sources

Belgian bovine veterinarian practices and opinions on udder health‐related antimicrobial use and services

Veterinary Record, EarlyView.
Abstract Background Changing legislation regarding antimicrobial consumption (AMC) forces Flemish bovine veterinary practitioners (BVP) to rethink their business models and shift their on‐farm practices from curative to preventive. However, little is known about their current practices and opinions regarding antibiotic stewardship, mastitis treatment ...
Lien Creytens, Sofie Piepers, Sarne De Vliegher   +2 more
wiley   +1 more source

Immune response to hepatitis B vaccination in HIV-positive individuals with isolated antibodies against hepatitis B core antigen: Results of a prospective Italian study.

PLoS ONE, 2017
Background and aimAntibodies against hepatitis B core antigen (anti-HBc) are found in 14-44% of patients with HIV infection, but it is still unclear whether hepatitis B virus (HBV) vaccination should be recommended for HIV-positive subjects with isolated
Giulia Morsica, Sabrina Bagaglio, Vincenzo Spagnuolo, Antonella Castagna, Clelia Di Serio, Andrea Galli, Liviana Della Torre, Andrea Andolina, Alexander Pramov, Caterina Uberti-Foppa   +9 more
doaj   +1 more source

Booster immunity – diagnosis of chronic hepatitis B viral infection

Journal of Infection in Developing Countries, 2019
Introduction: Diagnosis of chronic hepatitis B virus (HBV) infection particularly its occult form requires monitoring and repeat serological and molecular studies.
Radka T Komitova, Ani K Kevorkyan, Maria V Atanasova, Aneta V Ivanova, Elica Golkocheva-Markova   +4 more
doaj   +1 more source

Production and purification of chimeric HBc virus-like particles carrying influenza virus LAH domain as vaccine candidates [PDF]

, 2017
Background: The lack of a universal influenza vaccine is a global health problem. Interest is now focused on structurally conserved protein domains capable of eliciting protection against a broad range of influenza virus strains.
Akopjana, I, Blaha, B, Bogans, J, Crescente, V, de Obanos, MP, Farinelle, S, Kazaka, T, Kazaks, A, Kirsteina, A, Krimer, A, Lu, I-N, Mukhopadhyay, T, Muller, CP, Ogonah, O, Ose, V, Ramirez, A, Rosenberg, WM, Rowlands, DJ, Stonehouse, NJ, Tars, K   +19 more
core   +4 more sources

Lactate Accelerates Early Angiogenesis and Bone Regeneration Through Macrophage M1 Polarisation

Cell Proliferation, EarlyView.
During the early stage of bone defect healing, lactate accumulates and contributes to increasing NOD1 expression by stabilising HIF1α that in turn triggers a calcium influx, which ultimately polarises macrophages towards the M1 phenotype and accelerates vascularisation of endothelial cells.
Lulu Liu, Danning Ma, Jia Song, Boon Chin Heng, Ying Huang, Xuehui Zhang, Mingming Xu, Yan Wei, Tai Wei, Jinqi Wei, Xuliang Deng   +10 more
wiley   +1 more source

Prevalence of Hepatitis B Virus Markers in Patients with Autoimmune Inflammatory Rheumatic Diseases in Italy

Microorganisms, 2020
Chronic hepatitis B virus (HBV) infection may be reactivated by immunosuppressive drugs in patients with autoimmune inflammatory rheumatic diseases.
Marco Canzoni, Massimo Marignani, Maria Laura Sorgi, Paola Begini, Michela Ileen Biondo, Sara Caporuscio, Vincenzo Colonna, Francesca Della Casa, Paola Conigliaro, Cinzia Marrese, Eleonora Celletti, Irene Modesto, Mario Stefano Peragallo, Bruno Laganà, Andrea Picchianti-Diamanti, Roberta Di Rosa, Claudia Ferlito, Simonetta Salemi, Raffaele D’Amelio, Tommaso Stroffolini   +19 more
doaj   +1 more source