Results 191 to 200 of about 3,963,204 (295)

A single‐center prospective observational study evaluating the efficacy and safety of tirbanibulin 1% in actinic keratoses in immunosuppressed patients: the ESTIMATE study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background Actinic keratoses (AKs) are common precursors to squamous cell carcinoma and pose a heightened risk in immunosuppressed patients, such as organ transplant recipients (OTRs). Patients and methods This prospective, monocentric, single‐arm observational study investigated the safety and efficacy of topical tirbanibulin 1% ointment in ...
Elisa Zavattaro, Federica Veronese, Vanessa Tarantino, Chiara Airoldi, Paola Savoia   +4 more
wiley   +1 more source

Pre-exposure prophylaxis for prevention of HIV

An estimated 50,000 individuals become infected with the human immunodeficiency virus (HIV) in the United States annually. A new prevention strategy, Pre-exposure Prophylaxis (PrEP), is intended for high-risk populations to reduce their risk of becoming ...

core  

Capsid-Targeting Biologic Achieves Broad HIV-1 Neutralization with a High Barrier to Resistance. [PDF]

Int J Mol Sci
Stel FM, Zijlstra-Willems EM, Nuenen ACV, Boeser-Nunnink BDM, Geijtenbeek TBH, Kootstra NA.   +5 more
europepmc   +1 more source

Impact of Intensified Chemoimmunotherapy Regimens in Aggressive Non‐Hodgkin Lymphoma on Reproduction Patterns

European Journal of Haematology, EarlyView.
ABSTRACT Concerns about treatment‐related fertility impairment are common among young adult lymphoma survivors. Evidence on the impact of treatment for aggressive non‐Hodgkin lymphoma (NHL) on future childbearing is limited, although many individuals of reproductive age are affected.
Stefanie Antonilli, Anna Marklund, Joshua Entrop, Caroline E. Dietrich, Ingrid Glimelius, Tarec C. El‐Galaly, Alexander Fosså, Harald Holte, Karin E. Smedby, Knut B. Smeland, Sandra Eloranta   +10 more
wiley   +1 more source

HIV care continuum shows where improvement are needed

Infographic for World AIDS Day 2014 Vital signs: HIV care saves lives : viral suppression is key (Nov. 25, 2014).HIV care continuum shows where improvement are needed.Achieving viral suppression: more people with HIV need to be in medical care.HIV ...

core  

Product Nkabinde Mediates Cytokine Modulation and Antiviral Activity in HIV-Infected MT4 Cells. [PDF]

Int J Mol Sci
Setlhare B, Ngcobo M, Lustig G, Chikafu H, Zondo N, Nkabinde SA, Nkabinde M, Gqaleni N.   +7 more
europepmc   +1 more source

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

The FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini, Konstantinos Poalas, Margaux Versapuech, Clarisse Berlioz‐Torrent, Katy Janvier   +4 more
wiley   +1 more source

Daily pill can prevent HIV : reaching people who could benefit from PrEP

Preexposure prophylaxis (PrEP) is a medicine taken daily that can be used to prevent getting HIV. PrEP is for people without HIV who are at very high risk for getting it from sex or injection drug use.

core  

<i>Mycobacterium tuberculosis</i> and <i>Mycobacterium avium</i> Complex Cutaneous Co-Infection: Diagnostic and Therapeutic Challenges. [PDF]

Pathogens
Weng M, Zhou G, Wu Q, Chen Q, Li J, Wang Z, Li W.   +6 more
europepmc   +1 more source

Human APOBEC3G suppresses homologous recombination and LIG4‐independent end joining in DNA double‐strand break repair

The FEBS Journal, EarlyView.
Chromosomal DNA double‐strand breaks (DSBs) are repaired by homologous recombination and nonhomologous end joining (NHEJ). Recent work has additionally established theta‐mediated end‐joining (TMEJ) as a mechanism for DSB joining. Cells lacking NHEJ and TMEJ can repair DSBs in a homology‐dependent manner.
Shinta Saito, Miori Murayama, Usaki Arai, Sekifumi Akatsu, Ami Yamamoto, Misaki Kadoguchi, Noritaka Adachi   +6 more
wiley   +1 more source